Varaico: Literature-Extracted Genetic Variants

Gene:PTEN
Variant:p.K402R
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PTEN

NM_000314.8:p.K402R

Associated Papers

De novo NAD+ synthesis contributes to CD8+ T cell metabolic fitness and antitumor function.

Wan J et al.

Cell Reports, 2023

Neddylation of PTEN regulates its nuclear import and promotes tumor development.

Xie P et al.

Cell Research, 2021

Interactomic affinity profiling by holdup assay: Acetylation and distal residues impact the PDZome-binding specificity of PTEN phosphatase.

Jané P et al.

Plos One, 2020

PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.

Zhang J et al.

Cancer Discovery, 2019

Resveratrol regulates PTEN/Akt pathway through inhibition of MTA1/HDAC unit of the NuRD complex in prostate cancer.

Dhar S et al.

Biochimica Et Biophysica Acta, 2015

PTEN acetylation modulates its interaction with PDZ domain.

Ikenoue T et al.

Cancer Research, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."