Varaico: Literature-Extracted Genetic Variants

Gene:PTEN
Variant:p.V403A
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PTEN

NM_000314.8:p.V403A

Associated Papers

Targeted transcriptome analysis using synthetic long read sequencing uncovers isoform reprograming in the progression of colon cancer.

Liu S et al.

Communications Biology, 2021

33907296 (PubMed )
Supplement: 42003_2021_2024_MOESM10_ESM.xlsx › Supplementary_Data_7

Loss of PDZK1 expression activates PI3K/AKT signaling via PTEN phosphorylation in gastric cancer.

Zhao C et al.

Cancer Letters, 2019

Ezrin-radixin-moesin-binding phosphoprotein-50 regulates EGF-induced AKT activation through interaction with EGFR and PTEN.

Zheng J et al.

Oncology Reports, 2016

PTEN-PDZ domain interactions: binding of PTEN to PDZ domains of PTPN13.

Sotelo NS et al.

Methods (san Diego, Calif.), 2015

A functional network of the tumor suppressors APC, hDlg, and PTEN, that relies on recognition of specific PDZ-domains.

Sotelo NS et al.

Journal of Cellular Biochemistry, 2012

Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) is required for the estradiol-dependent increase of phosphatase and tensin homolog (PTEN) protein expression.

Yang L et al.

Endocrinology, 2011

PTEN acetylation modulates its interaction with PDZ domain.

Ikenoue T et al.

Cancer Research, 2008

Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.

Valiente M et al.

The Journal of Biological Chemistry, 2005

The human homologue of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer.

Liu Y et al.

Bmc Genetics, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."