Varaico: Literature-Extracted Genetic Variants

Gene:PTF1A
Variant:p.G12D
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PTF1A

NM_178161.3:p.G12D

Associated Papers

Discovery of a Linked Constellation of Gene Expression Revealed by Local Editing of Fibroblasts in Tumors.

Kuhn NF et al.

Biorxiv : the Preprint Server for Biology, 2025

COUP-TFII-mediated reprogramming of the vascular endothelium counteracts tumor immune evasion.

Zhu Y et al.

Nature Communications, 2025

A new effLuc/Kate dual reporter allele for tumor imaging in mice.

Bakiri L et al.

Disease Models & Mechanisms, 2025

Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer.

Wu Z et al.

Embo Reports, 2023

Autophagy loss impedes cancer-associated fibroblast activation via downregulating proline biosynthesis.

Bai J et al.

Autophagy, 2023

βig-h3-structured collagen alters macrophage phenotype and function in pancreatic cancer.

Bachy S et al.

Iscience, 2022

Multifaceted Functions of Protein Kinase D in Pathological Processes and Human Diseases.

Zhang X et al.

Biomolecules, 2021

A pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9-mediated somatic recombination.

Ideno N et al.

Laboratory Investigation; a Journal of Technical Methods and Pathology, 2019

The cornerstone K-RAS mutation in pancreatic adenocarcinoma: From cell signaling network, target genes, biological processes to therapeutic targeting.

Jonckheere N et al.

Critical Reviews in Oncology/hematology, 2017

A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics.

Ocal O et al.

Disease Models & Mechanisms, 2015

Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition.

Russell R et al.

Nature Communications, 2015

26220524 (PubMed )
Supplement: ncomms8677-s1.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."