Associated Papers
Rare loss-of-function mutations of PTGIR are enriched in fibromuscular dysplasia.
Georges A et al.
Cardiovascular Research, 2021
32531060 (PubMed )
Supplement: cvaa161_supplementary_data.docx
Comprehensive biochemical analysis of rare prostacyclin receptor variants: study of association of signaling with coronary artery obstruction.
Stitham J et al.
The Journal of Biological Chemistry, 2011
Differential association between human prostacyclin receptor polymorphisms and the development of venous thrombosis and intimal hyperplasia: a clinical biomarker study.
Patrignani P et al.
Pharmacogenetics and Genomics, 2008
Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: potential implications for cyclooxygenase-2 inhibition.
Arehart E et al.
Circulation Research, 2008
New insights into human prostacyclin receptor structure and function through natural and synthetic mutations of transmembrane charged residues.
Stitham J et al.
British Journal of Pharmacology, 2007
Arginine (CGC) codon targeting in the human prostacyclin receptor gene (PTGIR) and G-protein coupled receptors (GPCR).
Stitham J et al.
Gene, 2007
Genetic variation in G-protein-coupled receptors--consequences for G-protein-coupled receptors as drug targets.
Tang CM et al.
Expert Opinion on Therapeutic Targets, 2005
The unique ligand-binding pocket for the human prostacyclin receptor. Site-directed mutagenesis and molecular modeling.
Stitham J et al.
The Journal of Biological Chemistry, 2003
Impaired receptor binding and activation associated with a human prostacyclin receptor polymorphism.
Stitham J et al.
The Journal of Biological Chemistry, 2002
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