Associated Papers
Association Between Genetic Polymorphisms in the Prostaglandin Pathway and the Development of Patent Ductus Arteriosus in Preterm Infants.
Minta M et al.
International Journal of Molecular Sciences, 2025
Pharmacogenomics in cardiac therapy: Personalizing treatment for heart health.
Naderi N et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2025
Pharmacogenomics and genetic ancestry in Colombia: a study on all variant drug annotations of PharmGKB.
Acosta-Monterrosa AA et al.
Frontiers in Pharmacology, 2025
Genetic factors related to aspirin resistance using the Multiplate® device in Hong Kong Chinese patients with stable coronary heart disease.
Zeng W et al.
Heliyon, 2024
The PTGS1 (rs1330344) CC Genotype Contributes to Susceptibility to Kawasaki Disease in Southern Chinese Children.
Zheng H et al.
Angiology, 2023
Pharmacogenomics in Stroke and Cardiovascular Disease: State of the Art.
Ross S et al.
Stroke, 2023
Impact of pharmacogenetics on aspirin resistance: a systematic review.
Silva GFD et al.
Arquivos De Neuro-psiquiatria, 2023
Cardiovascular Pharmacogenomics: An Update on Clinical Studies of Antithrombotic Drugs in Brazilian Patients.
Hirata TDC et al.
Molecular Diagnosis & Therapy, 2021
PTGS1 gene variations associated with bleeding and platelet dysfunction.
Palma-Barqueros V et al.
Platelets, 2021
Identification of a homozygous recessive variant in PTGS1 resulting in a congenital aspirin-like defect in platelet function.
Chan MV et al.
Haematologica, 2021
A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant-negative effect on platelet function and bleeding diathesis.
Palma-Barqueros V et al.
American Journal of Hematology, 2021
Genetic polymorphisms associated with upper gastrointestinal bleeding: a systematic review.
Forgerini M et al.
The Pharmacogenomics Journal, 2021
Interaction of CYP2C19, P2Y12, and GPIIIa Variants Associates With Efficacy of Clopidogrel and Adverse Events on Patients With Ischemic Stroke.
Yi X et al.
Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/hemostasis, 2017
Genetic risk factors for myocardial infarction more clearly manifest for early age of first onset.
Titov BV et al.
Molecular Biology Reports, 2017
Cardiovascular pharmacogenetics: a promise for genomically-guided therapy and personalized medicine.
Zaiou M et al.
Clinical Genetics, 2017
Interactions among COX-2, GPIIIa and P2Y1 variants are associated with aspirin responsiveness and adverse events in patients with ischemic stroke.
Yi X et al.
Therapeutic Advances in Neurological Disorders, 2017
Interaction among COX-2, P2Y1 and GPIIIa gene variants is associated with aspirin resistance and early neurological deterioration in Chinese stroke patients.
Yi X et al.
Bmc Neurology, 2017
Association of polymorphisms of platelet receptors GPIa (807C>T), GPVI (13254T>C), and P2Y12 (34C>T and H1/H2 haplotype) with increased risk of periprocedural bleeding in patients undergoing coronary angiography/percutaneous coronary intervention.
Sionova M et al.
Postepy W Kardiologii Interwencyjnej = Advances in Interventional Cardiology, 2017
All too common: bleeding and genetic variation.
Johnsen JM
Journal of Thrombosis and Haemostasis : Jth, 2016
Combined variants in factor VIII and prostaglandin synthase-1 amplify hemorrhage severity across three generations of descendants.
Nance D et al.
Journal of Thrombosis and Haemostasis : Jth, 2016
Interaction between COX-1 and COX-2 Variants Associated with Aspirin Resistance in Chinese Stroke Patients.
Yi X et al.
Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association, 2016
The IL-1B Genetic Polymorphism Is Associated with Aspirin-Induced PepticUlcers in a Korean Ethnic Group.
Cho JH et al.
Gut and Liver, 2016
Association of single nucleotide polymorphisms in MPO and COX genes with oral lichen planus.
Wu D et al.
International Journal of Immunogenetics, 2015
Use of genetic data to guide therapy in arterial disease.
Ross S et al.
Journal of Thrombosis and Haemostasis : Jth, 2015
Influence of PTGS1, PTGFR, and MRP4 genetic variants on intraocular pressure response to latanoprost in Chinese primary open-angle glaucoma patients.
Gao LC et al.
European Journal of Clinical Pharmacology, 2015
Low-Dose Aspirin-Associated Upper and Mid Gastrointestinal Tract Damage and Gene Polymorphism.
Shiotani A et al.
Current Pharmaceutical Design, 2015
Variants of the Coagulation and Inflammation Genes Are Replicably Associated with Myocardial Infarction and Epistatically Interact in Russians.
Barsova RM et al.
Plos One, 2015
Genetic Variations in Inflammatory Response Genes and Their Association with the Risk of Prostate Cancer.
Cui X et al.
Biomed Research International, 2015
Effect of common single nucleotide polymorphisms in COX-1 gene on related metabolic activity in diabetic patients treated with acetylsalicylic acid.
Postula M et al.
Archives of Medical Science : Ams, 2014
The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.
Tang X et al.
Nucleic Acids Research, 2014
Single nucleotide polymorphism markers for low-dose aspirin-associated peptic ulcer and ulcer bleeding.
Shiotani A et al.
Journal of Gastroenterology and Hepatology, 2014
Novel non-synonymous polymorphisms in the COX-1 gene in Turkish pediatric patients with cardiovascular anomalies.
Coskun I et al.
Genetics and Molecular Research : Gmr, 2014
Genetic determinants of on-aspirin platelet reactivity: focus on the influence of PEAR1.
Würtz M et al.
Plos One, 2014
COX-1 (PTGS1) and COX-2 (PTGS2) polymorphisms, NSAID interactions, and risk of colon and rectal cancers in two independent populations.
Makar KW et al.
Cancer Causes & Control : Ccc, 2013
Value of platelet pharmacogenetics in common clinical practice of patients with ST-segment elevation myocardial infarction.
Verschuren JJ et al.
International Journal of Cardiology, 2013
Impact of genetic polymorphisms on adenoma recurrence and toxicity in a COX2 inhibitor (celecoxib) trial: results from a pilot study.
Kraus S et al.
Pharmacogenetics and Genomics, 2013
Expanding role of pharmacogenomics in the management of cardiovascular disorders.
Yip VL et al.
American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions, 2013
Interaction between ALOX5AP-SG13S114A/T and COX-2-765G/C increases susceptibility to cerebral infarction in a Chinese population.
Yi XY et al.
Genetics and Molecular Research : Gmr, 2013
Influence of genetic polymorphisms on platelet function, response to antiplatelet drugs and clinical outcomes in patients with coronary artery disease.
Tantry US et al.
Expert Review of Cardiovascular Therapy, 2013
PTGS1, PTGS2, ALOX5, ALOX12, ALOX15, and FLAP SNPs: interaction with fatty acids in colon cancer and rectal cancer.
Habermann N et al.
Genes & Nutrition, 2013
A meta-analysis of PTGS1 and PTGS2 polymorphisms and NSAID intake on the risk of developing cancer.
Nagao M et al.
Plos One, 2013
Novel single nucleotide polymorphism markers for low dose aspirin-associated small bowel bleeding.
Shiotani A et al.
Plos One, 2013
Decreased cyclooxygenase inhibition by aspirin in polymorphic variants of human prostaglandin H synthase-1.
Liu W et al.
Pharmacogenetics and Genomics, 2012
[Correlation analysis of aspirin resistance and cycloxygenase-1 haplotype in old Chinese patients with cardio-cerebrovascular diseases].
Li XL et al.
Zhongguo Ying Yong Sheng Li Xue Za Zhi = Zhongguo Yingyong Shenglixue Zazhi = Chinese Journal of Applied Physiology, 2012
Aspirin resistance: clinical significance and genetic polymorphism.
Xu ZH et al.
The Journal of International Medical Research, 2012
Genetic variation in inflammatory pathways is related to colorectal cancer survival.
Coghill AE et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2011
Genetic determinants of platelet reactivity during acetylsalicylic acid therapy in diabetic patients: evaluation of 27 polymorphisms within candidate genes.
Postula M et al.
Journal of Thrombosis and Haemostasis : Jth, 2011
Neurovascular coupling in the human visual cortex is modulated by cyclooxygenase-1 (COX-1) gene variant.
Hahn T et al.
Cerebral Cortex (new York, N.y. : 1991), 2011
A common promoter variant of the gene encoding cyclooxygenase-1 (PTGS1) is related to decreased incidence of myocardial infarction in patients with coronary artery disease.
Licis N et al.
Thrombosis Research, 2011