Varaico: Literature-Extracted Genetic Variants

Gene:PTGS1
Variant:p.L237M
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PTGS1

NM_000962.4:p.L237M

Associated Papers

The associations of candidate gene polymorphisms with aspirin resistance in patients with ischemic disease: a meta-analysis.

Li CX et al.

Human Genomics, 2024

The polygenic implication of clopidogrel responsiveness: Insights from platelet reactivity analysis and next-generation sequencing.

Echeverría O et al.

Plos One, 2024

38991024 (PubMed )
Supplement: pone.0306445.s008.xlsx › Supplementary_Table_6

Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia.

Fontana D et al.

Hemasphere, 2020

33196013 (PubMed )
Supplement: hs9-4-e497-s008.xlsx › Sheet1

rs5911 and rs3842788 Genetic Polymorphism, Blood Stasis Syndrome, and Plasma TXB2 and hs-CRP Levels Are Associated with Aspirin Resistance in Chinese Chronic Stable Angina Patients.

Xue M et al.

Evidence-based Complementary and Alternative Medicine : Ecam, 2017

Systematic meta-analyses and field synopsis of genetic association studies in colorectal adenomas.

Montazeri Z et al.

International Journal of Epidemiology, 2016

Effect of common single nucleotide polymorphisms in COX-1 gene on related metabolic activity in diabetic patients treated with acetylsalicylic acid.

Postula M et al.

Archives of Medical Science : Ams, 2014

COX-1 (PTGS1) and COX-2 (PTGS2) polymorphisms, NSAID interactions, and risk of colon and rectal cancers in two independent populations.

Makar KW et al.

Cancer Causes & Control : Ccc, 2013

PTGS1, PTGS2, ALOX5, ALOX12, ALOX15, and FLAP SNPs: interaction with fatty acids in colon cancer and rectal cancer.

Habermann N et al.

Genes & Nutrition, 2013

Decreased cyclooxygenase inhibition by aspirin in polymorphic variants of human prostaglandin H synthase-1.

Liu W et al.

Pharmacogenetics and Genomics, 2012

[Correlation analysis of aspirin resistance and cycloxygenase-1 haplotype in old Chinese patients with cardio-cerebrovascular diseases].

Li XL et al.

Zhongguo Ying Yong Sheng Li Xue Za Zhi = Zhongguo Yingyong Shenglixue Zazhi = Chinese Journal of Applied Physiology, 2012

Aspirin resistance: clinical significance and genetic polymorphism.

Xu ZH et al.

The Journal of International Medical Research, 2012

Genetic variation in inflammatory pathways is related to colorectal cancer survival.

Coghill AE et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2011

Genetic determinants of platelet reactivity during acetylsalicylic acid therapy in diabetic patients: evaluation of 27 polymorphisms within candidate genes.

Postula M et al.

Journal of Thrombosis and Haemostasis : Jth, 2011

Neurovascular coupling in the human visual cortex is modulated by cyclooxygenase-1 (COX-1) gene variant.

Hahn T et al.

Cerebral Cortex (new York, N.y. : 1991), 2011

A common promoter variant of the gene encoding cyclooxygenase-1 (PTGS1) is related to decreased incidence of myocardial infarction in patients with coronary artery disease.

Licis N et al.

Thrombosis Research, 2011

Genetic polymorphisms in inflammation pathway genes and prostate cancer risk.

Kwon EM et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2011

Polymorphisms in inflammatory pathway genes and their association with colorectal cancer risk.

Frank B et al.

International Journal of Cancer, 2010

Prostaglandin-endoperoxide synthase genes COX1 and COX2 - novel modifiers of disease severity in cystic fibrosis patients.

Czerska K et al.

Journal of Applied Genetics, 2010

Cyclooxygenase polymorphisms in gastric and colorectal carcinogenesis: are conclusive results available?

Pereira C et al.

European Journal of Gastroenterology & Hepatology, 2009

A review of gene-drug interactions for nonsteroidal anti-inflammatory drug use in preventing colorectal neoplasia.

Cross JT et al.

The Pharmacogenomics Journal, 2008

Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study.

Lee CR et al.

Clinical Pharmacology and Therapeutics, 2008

Genetic variability in prostaglandin synthesis, fish intake and risk of colorectal polyps.

Poole EM et al.

Carcinogenesis, 2007

Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1).

Lee CR et al.

Pharmacogenetics and Genomics, 2007

Polymorphisms in the genes involved in the arachidonic acid-pathway, fish consumption and the risk of colorectal cancer.

Siezen CL et al.

International Journal of Cancer, 2006

Prostacyclin synthase and arachidonate 5-lipoxygenase polymorphisms and risk of colorectal polyps.

Poole EM et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2006

Cyclooxygenase-1 haplotype modulates platelet response to aspirin.

Maree AO et al.

Journal of Thrombosis and Haemostasis : Jth, 2005

Cyclooxygenase-1 gene polymorphisms in patients with different asthma phenotypes and atopy.

Shi J et al.

The European Respiratory Journal, 2005

Colorectal adenoma risk is modified by the interplay between polymorphisms in arachidonic acid pathway genes and fish consumption.

Siezen CL et al.

Carcinogenesis, 2005

Arachidonate lipoxygenase (ALOX) and cyclooxygenase (COX) polymorphisms and colon cancer risk.

Goodman JE et al.

Carcinogenesis, 2004

Polymorphisms in PTGS1 (=COX-1) and risk of colorectal polyps.

Ulrich CM et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2004

Genetic variation in cyclooxygenase 1: effects on response to aspirin.

Halushka MK et al.

Clinical Pharmacology and Therapeutics, 2003

Mutations within the cyclooxygenase-1 gene in aspirin non-responders with recurrence of stroke.

Hillarp A et al.

Thrombosis Research, 2003

Cyclooxygenase 1 (COX1) polymorphisms in African-American and Caucasian populations.

Ulrich CM et al.

Human Mutation, 2002

[Cyclooxigenase-1 gene polymorphism and aspirin resistance].

Bondar' TN et al.

Tsitologiia I Genetika, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."