Varaico: Literature-Extracted Genetic Variants

Gene:PTGS1
Variant:p.V255V
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PTGS1

NM_000962.4:p.V255V

Associated Papers

Association of Single Nucleotide Polymorphisms in the Cyclooxygenase-2 (COX-2) Gene with Periodontal Disease-A Systematic Review with Meta-Analysis and Implications for Personalized Dentistry.

Savva V et al.

Journal of Personalized Medicine, 2025

Association between two single nucleotide polymorphisms of the Prostaglandin-Endoperoxide Synthase 1 and 2 genes and cell proliferative prostatic diseases in Lebanon.

Sheehan BJ et al.

Oncotarget, 2025

Two genome-wide interaction loci modify the association of nonsteroidal anti-inflammatory drugs with colorectal cancer.

Drew DA et al.

Science Advances, 2024

38809988 (PubMed )
Supplement: sciadv.adk3121_sm.pdf

Elevated Prostaglandin E2 Synthesis Is Associated with Clinical and Radiological Disease Severity in Cystic Fibrosis.

Gartner S et al.

Journal of Clinical Medicine, 2024

Mutation of the cyclooxygenase 2 gene promoter and anastomotic leakage in colorectal cancer patients: retrospective cohort study.

Grahn O et al.

Bjs Open, 2024

Influence of the Cyclooxygenase-2 Gene -765G/C and -1195G/A Polymorphisms on Development of Ischemic Stroke.

Wu G et al.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association, 2016

Functional polymorphisms of the cyclooxygenase-2 gene and prognosis of hepatocellular carcinoma - a cohort study in Chinese people.

Liang R et al.

Genetics and Molecular Research : Gmr, 2016

Lack of association between the cyclooxygenase 2 -765G>C polymorphism and prostate cancer risk: a meta-analysis.

Feng YQ et al.

Genetics and Molecular Research : Gmr, 2015

Cyclooxygenase-2 gene polymorphisms and the risk of colorectal cancer: A population-based study.

Li H et al.

Oncology Letters, 2015

Cyclooxygenase-2 polymorphisms and breast cancer associated risk in Pakistani patients.

Moatter T et al.

Pathology Oncology Research : Por, 2015

Cyclooxygenase-2 genetic variants influence intratumoral infiltration of Foxp3-positive regulatory T cells in non-small cell lung cancer.

Yukawa T et al.

Oncology Reports, 2015

COX-2 polymorphisms -765G→C and -1195A→G and hepatocellular carcinoma risk.

Gharib AF et al.

Gene, 2014

PTGS2 gene polymorphism -765G>C is associated with coronary artery disease: a meta-analysis.

Xuan CL et al.

Genetics and Molecular Research : Gmr, 2014

Meta-analysis of the association between COX-2 polymorphisms and risk of colorectal cancer based on case-control studies.

Peng Q et al.

Plos One, 2014

Functional promoter -765 G > C variant in COX-2 gene is associated with the susceptibility of breast cancer in Chinese Han women.

Gao J et al.

Cancer Cell International, 2014

COX-1 (PTGS1) and COX-2 (PTGS2) polymorphisms, NSAID interactions, and risk of colon and rectal cancers in two independent populations.

Makar KW et al.

Cancer Causes & Control : Ccc, 2013

Influence of Cyclooxygenase-2 (COX-2) gene promoter-1195 and allograft inflammatory factor-1 (AIF-1) polymorphisms on allograft outcome in Hispanic kidney transplant recipients.

Vu D et al.

Human Immunology, 2013

Cyclooxygenase 2 genetic polymorphism may increase the risk of developing leukoaraiosis in Chinese.

Shan XY et al.

Journal of Molecular Neuroscience : Mn, 2013

The association between cyclooxygenase-2 1195 G/A polymorphism and hepatocellular carcinoma: evidence from a meta-analysis.

Bu X et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2013

Association study of polymorphisms in the cyclooxygenase-2 gene and Alzheimer's disease risk in Chinese.

Tang W et al.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013

Cyclooxygenase-2 ( COX -2) gene-765G/C polymorphism and advanced-stage endometriosis in Korean women.

Kim HY et al.

American Journal of Reproductive Immunology (new York, N.y. : 1989), 2012

Functional polymorphism of cyclooxygenase-2 gene (G-765C) in chronic obstructive pulmonary disease patients.

Pietras T et al.

Molecular Biology Reports, 2012

Cyclooxygenase-2 polymorphisms and pancreatic cancer susceptibility.

Özhan G et al.

Pancreas, 2011

The cyclooxygenase-2-765C promoter polymorphism protects against the development of chronic obstructive pulmonary disease.

Wu L et al.

Respiratory Medicine, 2011

Cyclooxygenase-2 polymorphisms and susceptibility to esophageal cancer: a meta-analysis.

Liang Y et al.

The Tohoku Journal of Experimental Medicine, 2011

Functional polymorphisms of cyclooxygenase-2 gene and risk for hepatocellular carcinoma.

Akkız H et al.

Molecular and Cellular Biochemistry, 2011

A polymorphism in the cyclooxygenase 2 gene in type 1 diabetic patients with nephropathy.

Hubáček JA et al.

Physiological Research, 2011

Cyclooxygenase-2 gene promoter polymorphisms affect susceptibility to hepatitis C virus infection and disease progression.

Sakaki M et al.

Hepatology Research : the Official Journal of the Japan Society of Hepatology, 2010

Cyclooxygenase-2 polymorphisms and susceptibility to gastric carcinoma: a meta-analysis.

Liu JL et al.

World Journal of Gastroenterology, 2010

[Anxiety, depression and polymorphism of the gene encoding superoxide dismutase in patients with chronic obstructive pulmonary disease].

Pietras T et al.

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego, 2010

Functional variants of COX-2 and risk of tobacco-related oral squamous cell carcinoma in high-risk Asian Indians.

Mittal M et al.

Oral Oncology, 2010

Potentially functional COX-2-1195G>A polymorphism increases the risk of digestive system cancers: a meta-analysis.

Dong J et al.

Journal of Gastroenterology and Hepatology, 2010

COX-2 polymorphisms and colorectal cancer risk: a strategy for chemoprevention.

Pereira C et al.

European Journal of Gastroenterology & Hepatology, 2010

The effect of genetic polymorphisms of cyclooxygenase 2 on acute pancreatitis in Turkey.

Ozhan G et al.

Pancreas, 2010

Effect of COX2 -765G>C and c.3618A>G polymorphisms on the risk and survival of sporadic colorectal cancer.

Iglesias D et al.

Cancer Causes & Control : Ccc, 2009

Genetic polymorphisms in the cyclooxygenase-1 and cyclooxygenase-2 genes and risk of colorectal adenoma.

Gong Z et al.

International Journal of Colorectal Disease, 2009

Association of polymorphisms in cyclooxygenase (COX)-2 with coronary and carotid calcium in the Diabetes Heart Study.

Rudock ME et al.

Atherosclerosis, 2009

Common single nucleotide polymorphisms in cyclooxygenase-2 and risk of severe chronic periodontitis in a Chinese population.

Xie CJ et al.

Journal of Clinical Periodontology, 2009

Functional polymorphisms of the cyclooxygenase (PTGS2) gene and risk for gallbladder cancer in a North Indian population.

Srivastava K et al.

Journal of Gastroenterology, 2009

A review of gene-drug interactions for nonsteroidal anti-inflammatory drug use in preventing colorectal neoplasia.

Cross JT et al.

The Pharmacogenomics Journal, 2008

Genetic polymorphisms of cyclooxygenase-2 and colorectal adenoma risk: the Self Defense Forces Health Study.

Ueda N et al.

Cancer Science, 2008

Polymorphisms in PTGS1, PTGS2 and IL-10 do not influence colorectal adenoma recurrence in the context of a randomized aspirin intervention trial.

Hubner RA et al.

International Journal of Cancer, 2007

Association of prostaglandin-endoperoxide synthase 2 gene polymorphisms with asthma and atopy in Chinese children.

Chan IH et al.

Allergy, 2007

Associations of functional polymorphisms in cyclooxygenase-2 and platelet 12-lipoxygenase with risk of occurrence and advanced disease status of colorectal cancer.

Tan W et al.

Carcinogenesis, 2007

Functional polymorphisms in the cyclooxygenase 2 (COX-2) gene and risk of breast cancer in a Chinese population.

Gao J et al.

Journal of Toxicology and Environmental Health. Part A, 2007

Functional prostaglandin-endoperoxide synthase 2 polymorphism predicts poor outcome in sarcoidosis.

Hill MR et al.

American Journal of Respiratory and Critical Care Medicine, 2006

Protective effect of the G-765C COX-2 polymorphism on subclinical atherosclerosis and inflammatory markers in asymptomatic subjects with cardiovascular risk factors.

Orbe J et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2006

Genetic variants in cyclooxygenase-2: Expression and risk of gastric cancer and its precursors in a Chinese population.

Liu F et al.

Gastroenterology, 2006

Genetically mediated interindividual variation in analgesic responses to cyclooxygenase inhibitory drugs.

Lee YS et al.

Clinical Pharmacology and Therapeutics, 2006

Relationship between cyclooxygenase 8473T>C polymorphism and the risk of lung cancer: a case-control study.

Park JM et al.

Bmc Cancer, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."