Varaico: Literature-Extracted Genetic Variants

Gene:PTGS1
Variant:p.Q281R
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PTGS1

NM_000962.4:p.Q281R

Associated Papers

Clinical Application of Pharmacogenomics in Stroke Management: Current Evidence and Future Directions.

Lee KJ et al.

Journal of Stroke, 2026

Association between two single nucleotide polymorphisms of the Prostaglandin-Endoperoxide Synthase 1 and 2 genes and cell proliferative prostatic diseases in Lebanon.

Sheehan BJ et al.

Oncotarget, 2025

Genetic factors related to aspirin resistance using the Multiplate® device in Hong Kong Chinese patients with stable coronary heart disease.

Zeng W et al.

Heliyon, 2024

Impact of pharmacogenetics on aspirin resistance: a systematic review.

Silva GFD et al.

Arquivos De Neuro-psiquiatria, 2023

Molecular monitoring of patient response to painkiller drugs.

Ayuso P et al.

Expert Review of Molecular Diagnostics, 2022

Cardiovascular Pharmacogenomics: An Update on Clinical Studies of Antithrombotic Drugs in Brazilian Patients.

Hirata TDC et al.

Molecular Diagnosis & Therapy, 2021

Effect of 106PEAR1 and 168PTGS1 genetic polymorphisms on recurrent ischemic stroke in Chinese patient.

Zhao J et al.

Medicine, 2019

Aspirin & clopidogrel non-responsiveness & its association with genetic polymorphisms in patients with myocardial infarction.

Pandey CP et al.

The Indian Journal of Medical Research, 2019

COX-1 and COX-2 polymorphisms in susceptibility to cerebral palsy in very preterm infants.

Kapitanović Vidak H et al.

Molecular Neurobiology, 2017

Cardiovascular pharmacogenetics: a promise for genomically-guided therapy and personalized medicine.

Zaiou M et al.

Clinical Genetics, 2017

Association of polymorphisms of platelet receptors GPIa (807C>T), GPVI (13254T>C), and P2Y12 (34C>T and H1/H2 haplotype) with increased risk of periprocedural bleeding in patients undergoing coronary angiography/percutaneous coronary intervention.

Sionova M et al.

Postepy W Kardiologii Interwencyjnej = Advances in Interventional Cardiology, 2017

Use of genetic data to guide therapy in arterial disease.

Ross S et al.

Journal of Thrombosis and Haemostasis : Jth, 2015

Influence of PTGS1, PTGFR, and MRP4 genetic variants on intraocular pressure response to latanoprost in Chinese primary open-angle glaucoma patients.

Gao LC et al.

European Journal of Clinical Pharmacology, 2015

Value of platelet pharmacogenetics in common clinical practice of patients with ST-segment elevation myocardial infarction.

Verschuren JJ et al.

International Journal of Cardiology, 2013

Impact of genetic polymorphisms on adenoma recurrence and toxicity in a COX2 inhibitor (celecoxib) trial: results from a pilot study.

Kraus S et al.

Pharmacogenetics and Genomics, 2013

Expanding role of pharmacogenomics in the management of cardiovascular disorders.

Yip VL et al.

American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions, 2013

Influence of genetic polymorphisms on platelet function, response to antiplatelet drugs and clinical outcomes in patients with coronary artery disease.

Tantry US et al.

Expert Review of Cardiovascular Therapy, 2013

Aspirin resistance: clinical significance and genetic polymorphism.

Xu ZH et al.

The Journal of International Medical Research, 2012

Polymorphisms in inflammatory pathway genes and their association with colorectal cancer risk.

Frank B et al.

International Journal of Cancer, 2010

Platelet gene polymorphisms and risk of bleeding in patients undergoing elective coronary angiography: a genetic substudy of the PRAGUE-8 trial.

Motovska Z et al.

Atherosclerosis, 2010

Platelet pharmacogenomics.

Zuern CS et al.

Journal of Thrombosis and Haemostasis : Jth, 2010

Platelet glycoprotein GP VI 13254C allele is an independent risk factor of premature myocardial infarction.

Motovska Z et al.

Thrombosis Research, 2010

Genetic polymorphisms in the cyclooxygenase-1 and cyclooxygenase-2 genes and risk of colorectal adenoma.

Gong Z et al.

International Journal of Colorectal Disease, 2009

Pharmacogenetics of aspirin resistance: a comprehensive systematic review.

Goodman T et al.

British Journal of Clinical Pharmacology, 2008

Dose-related efficacy of aspirin after coronary surgery in patients With Pl(A2) polymorphism (NCT00262275).

Lim E et al.

The Annals of Thoracic Surgery, 2007

Effect of a specific cyclooxygenase-gene polymorphism (A-842G/C50T) on the occurrence of peptic ulcer hemorrhage.

van Oijen MG et al.

Digestive Diseases and Sciences, 2006

Cyclooxygenase-1 haplotype modulates platelet response to aspirin.

Maree AO et al.

Journal of Thrombosis and Haemostasis : Jth, 2005

Cyclooxygenase-1 gene polymorphisms in patients with different asthma phenotypes and atopy.

Shi J et al.

The European Respiratory Journal, 2005

Structural and catalytic polymorphism of human enzymes: Novel potential platforms for biomedical diagnostics.

Kurova VS et al.

Biotechnology Advances, 0

The cyclooxygenase-1 C50T polymorphism is not associated with aspirin responsiveness status in stable coronary artery disease in Tunisian patients.

Chakroun T et al.

Genetic Testing and Molecular Biomarkers, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."