Associated Papers
Osteomesopyknosis associated with a novel ALOX5 variant that impacts the RANKL pathway.
Fernandez-Luna JL et al.
Molecular Genetics & Genomic Medicine, 2024
Genetic analysis of four consanguineous multiplex families with inflammatory bowel disease.
Ben-Yosef N et al.
Gastroenterology Report, 2021
PTGS1 gene variations associated with bleeding and platelet dysfunction.
Palma-Barqueros V et al.
Platelets, 2021
Identification of a homozygous recessive variant in PTGS1 resulting in a congenital aspirin-like defect in platelet function.
Chan MV et al.
Haematologica, 2021
A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant-negative effect on platelet function and bleeding diathesis.
Palma-Barqueros V et al.
American Journal of Hematology, 2021
Deep sequencing of prostaglandin-endoperoxide synthase (PTGE) genes reveals genetic susceptibility for cross-reactive hypersensitivity to NSAID.
García-Martín E et al.
British Journal of Pharmacology, 2021
Application of whole-exome sequencing to direct the specific functional testing and diagnosis of rare inherited bleeding disorders in patients from the Öresund Region, Scandinavia.
Leinøe E et al.
British Journal of Haematology, 2017
Genetic polymorphisms of HO-1 and COX-1 are associated with aspirin resistance defined by light transmittance aggregation in Chinese Han patients.
Li XL et al.
Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/hemostasis, 2013
Decreased cyclooxygenase inhibition by aspirin in polymorphic variants of human prostaglandin H synthase-1.
Liu W et al.
Pharmacogenetics and Genomics, 2012
Prostaglandin-endoperoxide synthase genes COX1 and COX2 - novel modifiers of disease severity in cystic fibrosis patients.
Czerska K et al.
Journal of Applied Genetics, 2010
Cyclooxygenase polymorphisms in gastric and colorectal carcinogenesis: are conclusive results available?
Pereira C et al.
European Journal of Gastroenterology & Hepatology, 2009
Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1).
Lee CR et al.
Pharmacogenetics and Genomics, 2007
Cyclooxygenase-1 gene polymorphisms in patients with different asthma phenotypes and atopy.
Shi J et al.
The European Respiratory Journal, 2005
Arachidonate lipoxygenase (ALOX) and cyclooxygenase (COX) polymorphisms and colon cancer risk.
Goodman JE et al.
Carcinogenesis, 2004
Genetic variation in cyclooxygenase 1: effects on response to aspirin.
Halushka MK et al.
Clinical Pharmacology and Therapeutics, 2003
Mutations within the cyclooxygenase-1 gene in aspirin non-responders with recurrence of stroke.
Hillarp A et al.
Thrombosis Research, 2003
[Cyclooxigenase-1 gene polymorphism and aspirin resistance].
Bondar' TN et al.
Tsitologiia I Genetika, 0