Associated Papers
Genetic insights into migraine pathophysiology: COX-2 1195 A>G (rs689466) and COX-2 765 G>C (rs20417) polymorphisms and their clinical implications.
Mozaffari E et al.
Neurological Research, 2026
Functional insights into PTGS2 rs689466 polymorphism associated to asthma in West Bengal, India.
Ganai I et al.
Gene, 2025
A double-blind, randomized controlled study of the effects of celecoxib on clinical symptoms and cognitive impairment in patients with drug-naïve first episode schizophrenia: pharmacogenetic impact of cyclooxygenase-2 functional polymorphisms.
Wang DM et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 2024
The Role of Polymorphisms at the Interleukin-1, Interleukin-4, GATA-3 and Cyclooxygenase-2 Genes in Non-Surgical Periodontal Therapy.
Walther KA et al.
International Journal of Molecular Sciences, 2022
Cyclooxygenase-2 Gene Polymorphisms -765G>C and -1195A>G and Mycosis Fungoides Risk.
Sayed KS et al.
Dermatology (basel, Switzerland), 2021
Cyclooxygenase-2 haplotypes influence the longitudinal risk of malaria and severe malarial anemia in Kenyan children from a holoendemic transmission region.
Anyona SB et al.
Journal of Human Genetics, 2020
Systematic Review of Genetic Factors in the Etiology of Esophageal Squamous Cell Carcinoma in African Populations.
Simba H et al.
Frontiers in Genetics, 2019
The COX2 genetic variants in oral squamous cell carcinoma in Turkish population.
Cacina C et al.
Cellular and Molecular Biology (noisy-le-grand, France), 2018
PTGS2 polymorphism rs689466 favors breast cancer recurrence in obese patients.
Freitas-Alves DR et al.
Endocrine-related Cancer, 2018
Cyclooxygenase-2 (COX-2) gene polymorphism in patients with differentiated thyroid carcinomas in the Turkish population
Uçan B et al.
Turkish Journal of Medical Sciences, 2017
Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies.
Wang J et al.
Scientific Reports, 2017
Influence of Genetic Polymorphisms in Prostaglandin E2 Pathway (COX-2/HPGD/SLCO2A1/ABCC4) on the Risk for Colorectal Adenoma Development and Recurrence after Polypectomy.
Pereira C et al.
Clinical and Translational Gastroenterology, 2016
-1195 A/G promoter variants of the cyclooxygenase-2 gene increases the risk of pain occurrence in endometriotic women.
Wang H et al.
Clinical and Experimental Obstetrics & Gynecology, 2016
Cyclooxygenase-2 gene polymorphisms and risk of Alzheimer's disease: A meta-analysis.
Luo D et al.
Journal of the Neurological Sciences, 2015
The VEGFR2, COX-2 and MMP-2 polymorphisms are associated with clinical outcome of patients with inoperable non-small cell lung cancer.
Butkiewicz D et al.
International Journal of Cancer, 2015
Common Variants of the Prostaglandin-Endoperoxide Synthase 2 Gene and Hepatocellular Carcinoma Susceptibility.
Li HG et al.
Medicine, 2015
Reduced ex vivo stimulated IL-6 response in infants randomized to fish oil from 9 to 18 months, especially among PPARG2 and COX2 wild types.
Harsløf LB et al.
Prostaglandins, Leukotrienes, and Essential Fatty Acids, 2015
Cyclooxygenase-2 (COX2) gene polymorphisms and the risk of sporadic colorectal cancer and polyps among Jordanian population.
Shomaf M et al.
The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology, 2015
Genomic single nucleotide polymorphisms in the offspring of gastric cancer patients predispose to spasmolytic polypeptide-expressing metaplasia after H. pylori infection.
Tsai YC et al.
Journal of Biomedical Science, 2015
Five COX-2 gene polymorphisms and risk of breast cancer: an updated meta-analysis based on 19 case-control studies.
Li Q et al.
Medical Oncology (northwood, London, England), 2015
Functional Polymorphisms in COX-2 Gene Are Correlated with the Risk of Oral Cancer.
Li D et al.
Biomed Research International, 2015
Association of promoter polymorphism -765G>C in the PTGS2 gene with malignant melanoma in Italian patients and its correlation to gene expression in dermal fibroblasts.
Gomez-Lira M et al.
Experimental Dermatology, 2014
COX-2 polymorphisms -765G→C and -1195A→G and hepatocellular carcinoma risk.
Gharib AF et al.
Gene, 2014
The -1195G allele increases the transcriptional activity of cyclooxygenase-2 gene (COX-2) in colon cancer cell lines.
Pereira C et al.
Molecular Carcinogenesis, 2014
Study of the polymorphisms of cyclooxygenase-2 (-765G>C) and 5-lipoxygenase (1708G>A) in patients with colorectal cancer.
Pimenta CA et al.
Oncology Letters, 2014
Meta-analysis of the association between COX-2 polymorphisms and risk of colorectal cancer based on case-control studies.
Peng Q et al.
Plos One, 2014
Intestinal PTGS2 mRNA levels, PTGS2 gene polymorphisms, and colorectal carcinogenesis.
Vogel LK et al.
Plos One, 2014
The impact of PLA2G4A and PTGS2 gene polymorphisms, and red blood cell PUFAs deficit on niacin skin flush response in schizophrenia patients.
Nadalin S et al.
Prostaglandins, Leukotrienes, and Essential Fatty Acids, 2013
-765 G→C and -1195 A→G promoter variants of the cyclooxygenase-2 gene decrease the risk for preeclampsia.
Gurdol F et al.
Genetic Testing and Molecular Biomarkers, 2012
Cyclooxygenase-2 gene and lung carcinoma risk.
Coskunpinar E et al.
Medical Oncology (northwood, London, England), 2011
Functional genetic variations of cyclooxygenase-2 and susceptibility to acute myeloid leukemia in a Chinese population.
Zheng J et al.
European Journal of Haematology, 2011
Population-specific genetic associations with oesophageal squamous cell carcinoma in South Africa.
Bye H et al.
Carcinogenesis, 2011
Analysis of the 3'UTR of the prostaglandin synthetase-2 (PTGS-2/COX-2) gene in non-melanoma skin cancer after organ transplantation.
Gomez-Lira M et al.
Experimental Dermatology, 2011
The Cox-2 -1195 G > A polymorphism and cancer risk: a meta-analysis of 25 case-control studies.
Tang Z et al.
Mutagenesis, 2011
Polymorphic human prostaglandin H synthase-2 proteins and their interactions with cyclooxygenase substrates and inhibitors.
Liu W et al.
The Pharmacogenomics Journal, 2011
Cyclooxygenase-2 gene and epithelial ovarian carcinoma risk.
Agachan Cakmakoglu B et al.
Molecular Biology Reports, 2011
Cyclooxygenase-2 (COX-2) polymorphisms and risk of inflammatory bowel disease in a Scottish and Danish case-control study.
Andersen V et al.
Inflammatory Bowel Diseases, 2011
Comprehensive association analysis of candidate genes for generalized vitiligo supports XBP1, FOXP3, and TSLP.
Birlea SA et al.
The Journal of Investigative Dermatology, 2011
Functional polymorphisms of cyclooxygenase-2 gene and risk for hepatocellular carcinoma.
Akkız H et al.
Molecular and Cellular Biochemistry, 2011
The functional -765G→C polymorphism of the COX-2 gene may reduce the risk of developing crohn's disease.
de Vries HS et al.
Plos One, 2010
Polymorphisms in inflammatory genes, plasma antioxidants, and prostate cancer risk.
Zhang J et al.
Cancer Causes & Control : Ccc, 2010
Functional variants of COX-2 and risk of tobacco-related oral squamous cell carcinoma in high-risk Asian Indians.
Mittal M et al.
Oral Oncology, 2010
COX-2 polymorphisms and colorectal cancer risk: a strategy for chemoprevention.
Pereira C et al.
European Journal of Gastroenterology & Hepatology, 2010
COX-2 polymorphisms -765G-->C and -1195A-->G and colorectal cancer risk.
Hoff JH et al.
World Journal of Gastroenterology, 2009
COX-2 polymorphisms and the risk for head and neck cancer in white patients.
Peters WH et al.
Head & Neck, 2009
The polymorphism IL-1beta T-31C is associated with a longer overall survival in patients with multiple myeloma undergoing auto-SCT.
Vangsted AJ et al.
Bone Marrow Transplantation, 2009
Association of COX2 functional polymorphisms and the risk of vitiligo in Chinese populations.
Li M et al.
Journal of Dermatological Science, 2009
Up-regulation of inflammatory signalings by areca nut extract and role of cyclooxygenase-2 -1195G>a polymorphism reveal risk of oral cancer.
Chiang SL et al.
Cancer Research, 2008
[Association between single nucleotide polymorphisms in the promoter of cyclooxygenase COX-2 gene and hereditary susceptibility to pancreatic cancer].
Xu DK et al.
Zhonghua Yi Xue Za Zhi, 2008