Associated Papers
Pharmacological targeting PTK6 inhibits the JAK2/STAT3 sustained stemness and reverses chemoresistance of colorectal cancer.
Liu C et al.
Journal of Experimental & Clinical Cancer Research : Cr, 2021
PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer.
Wozniak DJ et al.
Nature Communications, 2017
PTK6 promotes degradation of c-Cbl through PTK6-mediated phosphorylation.
Kang SA et al.
Biochemical and Biophysical Research Communications, 2013
Constitutive activation of breast tumor kinase accelerates cell migration and tumor growth in vivo.
Miah S et al.
Oncogenesis, 2012
Interactions of STAP-2 with Brk and STAT3 participate in cell growth of human breast cancer cells.
Ikeda O et al.
The Journal of Biological Chemistry, 2010
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1.
Kang SA et al.
The Journal of Biological Chemistry, 2010
Identification of STAT3 as a specific substrate of breast tumor kinase.
Liu L et al.
Oncogene, 2006
An intramolecular interaction between SH2-kinase linker and kinase domain is essential for the catalytic activity of protein-tyrosine kinase-6.
Kim HIe et al.
The Journal of Biological Chemistry, 2005
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