Varaico: Literature-Extracted Genetic Variants

Gene:PTP4A3
Variant:p.C104S
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PTP4A3

NM_032611.3:p.C104S

Associated Papers

PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation.

Johansson JA et al.

Developmental Cell, 2020

32652076 (PubMed )
Supplement: mmc1.pdf

Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) promotes the aggressiveness of human uveal melanoma through dephosphorylation of CRMP2.

Duciel L et al.

Scientific Reports, 2019

Increased expression of GATA zinc finger domain containing 1 through gene amplification promotes liver cancer by directly inducing phosphatase of regenerating liver 3.

Sun W et al.

Hepatology (baltimore, Md.), 2018

PRL-3 disrupts epithelial architecture by altering the post-mitotic midbody position.

Luján P et al.

Journal of Cell Science, 2016

The metastasis-promoting phosphatase PRL-3 shows activity toward phosphoinositides.

McParland V et al.

Biochemistry, 2011

Downregulation of p53 by phosphatase of regenerating liver 3 is mediated by MDM2 and PIRH2.

Min SH et al.

Life Sciences, 2010

[Construction and expression of PRL-3 plasmid with C104S point mutation and CAAX deletion].

Li WJ et al.

Beijing Da Xue Xue Bao. Yi Xue Ban = Journal of Peking University. Health Sciences, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."