Associated Papers
Structures of human protein tyrosine phosphatase variants reveal targetable allosteric sites.
Perdikari A et al.
The Journal of Biological Chemistry, 2025
Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy.
Perdikari A et al.
Biorxiv : the Preprint Server for Biology, 2025
Hereditable variants of classical protein tyrosine phosphatase genes: Will they prove innocent or guilty?
Hendriks WJAJ et al.
Frontiers in Cell and Developmental Biology, 2022
PhosphoPICK-SNP: quantifying the effect of amino acid variants on protein phosphorylation.
Patrick R et al.
Bioinformatics (oxford, England), 2017
Protein tyrosine phosphatase variants in human hereditary disorders and disease susceptibilities.
Hendriks WJ et al.
Biochimica Et Biophysica Acta, 2013
The 981C>T polymorphism in protein tyrosine phosphatase 1B is associated with decreased risk of coronary artery disease in Chinese Han population.
Zhou X et al.
Atherosclerosis, 2011
Lack of association of PTPN1 gene polymorphisms with type 2 diabetes in south Indians.
Bodhini D et al.
Journal of Genetics, 2011
Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.
Ryu GM et al.
Nucleic Acids Research, 2009
Discovery of a novel competitive inhibitor of PTP1B by high-throughput screening.
Shi L et al.
Acta Pharmacologica Sinica, 2008
Polymorphisms within the protein tyrosine phosphatase 1B (PTPN1) gene promoter: functional characterization and association with type 2 diabetes and related metabolic traits.
Meshkani R et al.
Clinical Chemistry, 2007
Lack of association between polymorphisms in the gene encoding protein tyrosine phosphatase 1B (PTPN1) and risk of Type 2 diabetes.
Wanic K et al.
Diabetic Medicine : a Journal of the British Diabetic Association, 2007
Protein tyrosine phosphatase 1B is not a major susceptibility gene for type 2 diabetes mellitus or obesity among Pima Indians.
Traurig M et al.
Diabetologia, 2007
Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associated phenotypes in the French population.
Cheyssac C et al.
Bmc Medical Genetics, 2006
Genetic association, post-translational modification, and protein-protein interactions in Type 2 diabetes mellitus.
Sharma A et al.
Molecular & Cellular Proteomics : Mcp, 2005
Association testing of the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes in 7,883 people.
Florez JC et al.
Diabetes, 2005
Protein tyrosine phosphatase 1B variant associated with fat distribution and insulin metabolism.
Ukkola O et al.
Obesity Research, 2005
The Pro387Leu variant of protein tyrosine phosphatase-1B is not associated with diabetes mellitus type 2 in a German population.
Gouni-Berthold I et al.
Journal of Internal Medicine, 2005
Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes.
Bento JL et al.
Diabetes, 2004
Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study.
Palmer ND et al.
Diabetes, 2004
Single nucleotide polymorphisms in protein tyrosine phosphatase 1beta (PTPN1) are associated with essential hypertension and obesity.
Olivier M et al.
Human Molecular Genetics, 2004
Paralysis as first manifestation of primary aldosteronism.
Karagiannis A et al.
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association, 2004
Lack of evidence for the 1484insG variant at the 3'-UTR of the protein tyrosine phosphatase 1B (PTP1B) gene as a genetic determinant of diabetic nephropathy development in type 1 diabetic patients.
De Cosmo S et al.
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association, 2004
Tyrosine phosphatase 1B and leptin receptor genes and their interaction in type 2 diabetes.
Santaniemi M et al.
Journal of Internal Medicine, 2004
Single nucleotide polymorphisms of protein tyrosine phosphatase 1B gene are associated with obesity in morbidly obese French subjects.
Kipfer-Coudreau S et al.
Diabetologia, 2004
Missense mutation of Pro387Leu in protein tyrosine phosphatase-1B (PTP-1B) is not associated with type 2 diabetes in a Chinese Han population.
Weng J et al.
Diabetes Care, 2003
A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro.
Echwald SM et al.
Diabetes, 2002
Protein tyrosine phosphatase 1B gene polymorphisms and essential hypertension: a case-control study in Chinese population.
Gu P et al.
Journal of Endocrinological Investigation, 0