Varaico: Literature-Extracted Genetic Variants

Gene:PTPN12
Variant:p.H230Y
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PTPN12

NM_002835.4:p.H230Y

Associated Papers

Evolutionarily Conserved Allosteric Communication in Protein Tyrosine Phosphatases.

Hjortness MK et al.

Biochemistry, 2018

30289703 (PubMed )
Supplement: bi8b00656_si_004.xlsx › Table_S5B

Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer.

Nair A et al.

Nature Medicine, 2018

Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase.

Sun T et al.

Cell, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."