Associated Papers
The desulfinylation enzyme sulfiredoxin-1 attenuates HSC activation and liver fibrosis by modulating the PTPN12-NLRP3 axis.
Kim JW et al.
Hepatology (baltimore, Md.), 2025
GABAB1e promotes the malignancy of human cancer cells by targeting the tyrosine phosphatase PTPN12.
Wei B et al.
Iscience, 2021
Structure and Molecular Dynamics Simulations of Protein Tyrosine Phosphatase Non-Receptor 12 Provide Insights into the Catalytic Mechanism of the Enzyme.
Dong H et al.
International Journal of Molecular Sciences, 2017
PTP-PEST targets a novel tyrosine site in p120 catenin to control epithelial cell motility and Rho GTPase activity.
Espejo R et al.
Journal of Cell Science, 2014
Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase.
Sun T et al.
Cell, 2011
Preliminary evidence for interaction of PTPN12 polymorphism with TSHR genotype and association with Graves' ophthalmopathy.
Syed AA et al.
Clinical Endocrinology, 2007
The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis.
Dubois MJ et al.
Nature Medicine, 2006
Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation.
Badour K et al.
The Journal of Experimental Medicine, 2004
Intact LIM 3 and LIM 4 domains of paxillin are required for the association to a novel polyproline region (Pro 2) of protein-tyrosine phosphatase-PEST.
Côté JF et al.
The Journal of Biological Chemistry, 1999
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