Associated Papers
Haploinsufficiency in PTPN2 leads to early-onset systemic autoimmunity from Evans syndrome to lupus.
Jeanpierre M et al.
The Journal of Experimental Medicine, 2024
Case report: JAK inhibitor treatment of immune dysregulation symptoms in a patient with PTPN2 deficiency.
Roppelt A et al.
Frontiers in Immunology, 2024
A homozygous missense variant in PTPN2 with early-onset Crohn's disease, growth failure and dysmorphic features in an infant: a case report.
Awwad J et al.
Journal of Genetics, 2023
Structural characterization of a pathogenic mutant of human protein tyrosine phosphatase PTPN2 (Cys216Gly) that causes very early onset autoimmune enteropathy.
Nian Q et al.
Protein Science : a Publication of the Protein Society, 2022
Hereditable variants of classical protein tyrosine phosphatase genes: Will they prove innocent or guilty?
Hendriks WJAJ et al.
Frontiers in Cell and Developmental Biology, 2022
T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling.
Marchelletta RR et al.
The Journal of Clinical Investigation, 2021
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