Varaico: Literature-Extracted Genetic Variants

Gene:PTPN21
Variant:p.C1108S
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PTPN21

NM_007039.4:p.C1108S

Associated Papers

Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.

Chen L et al.

Science Advances, 2024

PTPN21 and Hook3 relieve KIF1C autoinhibition and activate intracellular transport.

Siddiqui N et al.

Nature Communications, 2019

PTPN21 exerts pro-neuronal survival and neuritic elongation via ErbB4/NRG3 signaling.

Plani-Lam JH et al.

The International Journal of Biochemistry & Cell Biology, 2015

PTPD1 supports receptor stability and mitogenic signaling in bladder cancer cells.

Carlucci A et al.

The Journal of Biological Chemistry, 2010

Protein-tyrosine phosphatase PTPD1 regulates focal adhesion kinase autophosphorylation and cell migration.

Carlucci A et al.

The Journal of Biological Chemistry, 2008

Protein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinases.

Jui HY et al.

The Journal of Biological Chemistry, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."