Varaico: Literature-Extracted Genetic Variants

Gene:PTPN22
Variant:p.Y536F
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PTPN22

NM_015967.8:p.Y536F

Associated Papers

Tyrosine phosphatase PTPN22: multifunctional regulator of immune signaling, development, and disease.

Bottini N et al.

Annual Review of Immunology, 2014

Autoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residue.

Fiorillo E et al.

The Journal of Biological Chemistry, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."