Associated Papers
Association of PTPN22 single nucleotide polymorphisms (-1123G/C, +788G/A and +1858C/T) with inflammatory bowel disease.
ElMelegy TTH et al.
The Egyptian Journal of Immunology, 2025
Exploring the impact of SNPs rs2476601, rs2488457, and rs33996649 on PTPN22 expression, structure, and anti-CCP level in rheumatoid arthritis of the Indian population: a case-control and computational study.
Aswini S et al.
Frontiers in Medicine, 2025
Sjogren's syndrome: Everything you always wanted to know about genetic and epigenetic factors.
Perricone C et al.
Autoimmunity Reviews, 2024
The landscape of rare genetic variants in familial Waldenström macroglobulinemia.
Pemov A et al.
Blood Neoplasia, 2024
Interactions between TNFAIP3, PTPN22, and TRAF1-C5 gene polymorphisms in patients with primary Sjögren's syndrome.
Cadena-Sandoval D et al.
Archives of Rheumatology, 2024
Regulation of T Cell Signaling and Immune Responses by PTPN22.
Brownlie RJ et al.
Molecular and Cellular Biology, 2024
Analysis of IL-1β, TGF-β, IL-5, ACE, PTPN22 gene polymorphisms, and gene expression levels in Turkish children with IgA vasculitis.
Taşkın RB et al.
Molecular Biology Reports, 2023
Analysis of PTPN22 -1123 G>C, +788 G>A and +1858 C>T Polymorphisms in Patients with Primary Sjögren's Syndrome.
Menchaca-Tapia PA et al.
Diagnostics (basel, Switzerland), 2023
Genetic Polymorphism of PTPN22 in Autoimmune Diseases: A Comprehensive Review.
Tizaoui K et al.
Medicina (kaunas, Lithuania), 2022
Immunogenetics of Lupus Erythematosus.
Ünlü B et al.
Advances in Experimental Medicine and Biology, 2022
Hereditable variants of classical protein tyrosine phosphatase genes: Will they prove innocent or guilty?
Hendriks WJAJ et al.
Frontiers in Cell and Developmental Biology, 2022
Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an In-Silico Approach.
Akhtar M et al.
Biology, 2021
PTPN22 gene functional polymorphism (rs2476601) in older adults with frailty syndrome.
Rabaneda-Bueno R et al.
Molecular Biology Reports, 2021
Association of PTPN22-C1858T Polymorphism With Susceptibility to Mycobacterium tuberculosis and Mycobacterium leprae Infection: A Meta-Analysis.
Li S et al.
Frontiers in Immunology, 2021
Influence of PTPN22 Allotypes on Innate and Adaptive Immune Function in Health and Disease.
Armitage LH et al.
Frontiers in Immunology, 2021
PTPN22 Gene Polymorphisms in Pediatric Systemic Lupus Erythematosus.
Bahrami T et al.
Fetal and Pediatric Pathology, 2020
Multiple Sclerosis patients carry an increased burden of exceedingly rare genetic variants in the inflammasome regulatory genes.
Vidmar L et al.
Scientific Reports, 2019
PTPN22 +788 G>A (R263Q) Polymorphism is Associated with mRNA Expression but it is not a Susceptibility Marker for Rheumatoid Arthritis Patients from Western Mexico.
Ramírez-Pérez S et al.
Biochemical Genetics, 2019
Region 1p13.2 including the RSBN1, PTPN22, AP4B1 and long non-coding RNA genes does not bear risk factors for endemic pemphigus foliaceus (fogo selvagem).
Lobo-Alves SC et al.
International Journal of Immunogenetics, 2019
An association study in PTPN22 suggests that is a risk factor to Takayasu's arteritis.
Soto ME et al.
Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.], 2019
Role of genetic variability in Mendelian and multifactorial diseases.
Ramírez-Bello J
Gaceta Medica De Mexico, 2019
Evolutionarily Conserved Allosteric Communication in Protein Tyrosine Phosphatases.
Hjortness MK et al.
Biochemistry, 2018
The potential of PTPN22 as a therapeutic target for rheumatoid arthritis.
Carmona FD et al.
Expert Opinion on Therapeutic Targets, 2018
Tumor necrosis factor (TNF) and TNFR1 polymorphisms are not risk factors for rheumatoid arthritis in a Mexican population.
Cadena-Sandoval D et al.
Molecular Biology Reports, 2018
The VEGFA -1154G/A polymorphism is associated with reduced risk of rheumatoid arthritis but not with systemic lupus erythematosus in Mexican women.
Ramírez-Bello J et al.
The Journal of Gene Medicine, 2018
Association of PTPN22 gene polymorphism with non-segmental vitiligo in South Indian Tamils.
Rajendiran KS et al.
Postepy Dermatologii I Alergologii, 2018
Association between the functional PTPN22 G788A (R263Q) polymorphism and susceptibility to autoimmune diseases: A meta-analysis.
Bae SC et al.
Cellular and Molecular Biology (noisy-le-grand, France), 2018
The KCNQ1 gene polymorphism as a shared genetic risk for rheumatoid arthritis and chronic periodontitis in Japanese adults: A pilot case-control study.
Kobayashi T et al.
Journal of Periodontology, 2018
High prevalence of protein tyrosine phosphatase non-receptor N22 gene functional variant R620W in systemic lupus erythematosus patients from Kuwait: implications for disease susceptibility.
Al-Awadhi AM et al.
Bmc Rheumatology, 2018
Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) gene single nucleotide polymorphisms and its interaction with T2DM on pulmonary tuberculosis in Chinese Uygur population.
Wang XH et al.
Oncotarget, 2017
The PTPN22 R263Q polymorphism confers protection against systemic lupus erythematosus and rheumatoid arthritis, while PTPN22 R620W confers susceptibility to Graves' disease in a Mexican population.
López-Cano DJ et al.
Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.], 2017
Association of PTPN22 Single Nucleotide Polymorphisms with Celiac Disease.
Aflatounian M et al.
Fetal and Pediatric Pathology, 2017
PTPN22 Single-Nucleotide Polymorphisms in Iranian Patients with Type 1 Diabetes Mellitus.
Abbasi F et al.
Immunological Investigations, 2017
rs2476601 polymorphism in PTPN22 is associated with Crohn's disease but not with ulcerative colitis: a meta-analysis of 16,838 cases and 13,356 controls.
Hedjoudje A et al.
Annals of Gastroenterology, 2017
PTPN22 inhibition resets defective human central B cell tolerance.
Schickel JN et al.
Science Immunology, 2016
Association between a Functional HLA-G 14-bp Insertion/deletion Polymorphism and Susceptibility to Autoimmune Diseases: A Meta-analysis.
Lee YH et al.
Cellular and Molecular Biology (noisy-le-grand, France), 2015
Immunogenetics of systemic lupus erythematosus: A comprehensive review.
Ghodke-Puranik Y et al.
Journal of Autoimmunity, 2015
Role of PTPN22 and CSK gene polymorphisms as predictors of susceptibility and clinical heterogeneity in patients with Henoch-Schönlein purpura (IgA vasculitis).
López-Mejías R et al.
Arthritis Research & Therapy, 2015
Application of whole genome and RNA sequencing to investigate the genomic landscape of common variable immunodeficiency disorders.
van Schouwenburg PA et al.
Clinical Immunology (orlando, Fla.), 2015
Genetic variants within the TNFRSF1B gene and susceptibility to rheumatoid arthritis and response to anti-TNF drugs: a multicenter study.
Canet LM et al.
Pharmacogenetics and Genomics, 2015
Association between a gain-of-function variant of PTPN22 and rejection in liver transplantation.
Dullin R et al.
Transplantation, 2015
Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes.
Prescott NJ et al.
Plos Genetics, 2015
Low Frequencies of Autoimmunity-Associated PTPN22 Polymorphisms in MODY Patients, Including Those Transiently Expressing Islet Cell Autoantibodies.
Heneberg P et al.
International Archives of Allergy and Immunology, 2015
The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.
Tang X et al.
Nucleic Acids Research, 2014
PTPN22: the archetypal non-HLA autoimmunity gene.
Stanford SM et al.
Nature Reviews. Rheumatology, 2014
Systemic Lupus Erythematosus: Old and New Susceptibility Genes versus Clinical Manifestations.
J de AS et al.
Current Genomics, 2014
Tyrosine phosphatase PTPN22: multifunctional regulator of immune signaling, development, and disease.
Bottini N et al.
Annual Review of Immunology, 2014