Varaico: Literature-Extracted Genetic Variants

Gene:PTPN3
Variant:p.L232R
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PTPN3

NM_002829.4:p.L232R

Associated Papers

PTPN3 acts as a tumor suppressor and boosts TGF-β signaling independent of its phosphatase activity.

Yuan B et al.

The Embo Journal, 2019

Activating mutations in PTPN3 promote cholangiocarcinoma cell proliferation and migration and are associated with tumor recurrence in patients.

Gao Q et al.

Gastroenterology, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."