Varaico: Literature-Extracted Genetic Variants

Gene:PTPN6
Variant:p.V451M
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PTPN6

NM_002831.6:p.V451M

Associated Papers

Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL.

Schrader A et al.

Nature Communications, 2018

29449575 (PubMed )
Supplement: 41467_2017_2688_MOESM20_ESM.xlsx › b__Freq_TP096

A missense methionine mutation augments catalytic activity but reduces thermal stability in two protein tyrosine phosphatases.

Bishop AC

Biochemical and Biophysical Research Communications, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."