Varaico: Literature-Extracted Genetic Variants

Gene:PTPN9
Variant:p.D470A
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PTPN9

NM_002833.4:p.D470A

Associated Papers

PTPN9 dephosphorylates IGF1RY1165/1166 and alleviates IGF1R-mediated resistance to tyrosine kinase inhibitor in cholangiocarcinoma.

Hu JM et al.

Journal of Experimental & Clinical Cancer Research : Cr, 2025

PTPN9-mediated dephosphorylation of VTI1B promotes ATG16L1 precursor fusion and autophagosome formation.

Chou HY et al.

Autophagy, 2021

Protein-tyrosine phosphatase PTPN9 negatively regulates ErbB2 and epidermal growth factor receptor signaling in breast cancer cells.

Yuan T et al.

The Journal of Biological Chemistry, 2010

Control of vesicle fusion by a tyrosine phosphatase.

Huynh H et al.

Nature Cell Biology, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."