Varaico: Literature-Extracted Genetic Variants

Gene:PTPRC
Variant:p.P301S
Back to variants list

PTPRC

NM_002838.5:p.P301S

Associated Papers

Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes.

Guo JL et al.

Cell, 2025

Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.

Litvinchuk A et al.

Neuron, 2024

Parenchymal border macrophages regulate tau pathology and tau-mediated neurodegeneration.

Drieu A et al.

Life Science Alliance, 2023

Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy.

Chen X et al.

Nature, 2023

APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer's disease pathology and brain diseases.

Fernández-Calle R et al.

Molecular Neurodegeneration, 2022

Alzheimer's Retinopathy: Seeing Disease in the Eyes.

Mirzaei N et al.

Frontiers in Neuroscience, 2020

Oligomeric tau-targeted immunotherapy in Tg4510 mice.

Schroeder S et al.

Alzheimer's Research & Therapy, 2017

Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis.

Selenica ML et al.

Journal of Neuroinflammation, 2014

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."