Varaico: Literature-Extracted Genetic Variants

Gene:PTPRJ
Variant:p.R326Q
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PTPRJ

NM_002843.4:p.R326Q

Associated Papers

Being precise with anticoagulation to reduce adverse drug reactions: are we there yet?

Cross B et al.

The Pharmacogenomics Journal, 2024

The effects of CD148 Q276P/R326Q polymorphisms in A431D epidermoid cancer cell proliferation and epidermal growth factor receptor signaling.

He L et al.

Cancer Reports (hoboken, N.j.), 2022

Hereditable variants of classical protein tyrosine phosphatase genes: Will they prove innocent or guilty?

Hendriks WJAJ et al.

Frontiers in Cell and Developmental Biology, 2022

36755664 (PubMed )
Supplement: Table1.XLSX › Suppl_Table_1

Discovering Genotype Variants in an Infant with VACTERL through Clinical Exome Sequencing: A Support for Personalized Risk Assessment and Disease Prevention.

Pelizzo G et al.

Pediatric Reports, 2021

Genomic profiling of colorectal cancer with isolated lung metastasis.

Zhang N et al.

Cancer Cell International, 2020

32624706 (PubMed )
Supplement: 12935_2020_1373_MOESM3_ESM.xlsx › Sheet1

Comments on: "Meta-analysis of association between Arg326Gln (rs1503185) and Gln276Pro (rs1566734) polymorphisms of PTPRJ gene and cancer risk".

Gholami M et al.

Journal of Applied Genetics, 2019

A missense variant in PTPN12 associated with the risk of colorectal cancer by modifying Ras/MEK/ERK signaling.

Shen N et al.

Cancer Epidemiology, 2019

Increased burden of rare deleterious variants of the KCNQ1 gene in patients with large‑vessel ischemic stroke.

Janicki PK et al.

Molecular Medicine Reports, 2019

30816480 (PubMed )
Supplement: supplement_2.pdf

Meta-analysis of association between Arg326Gln (rs1503185) and Gln276Pro (rs1566734) polymorphisms of PTPRJ gene and cancer risk.

Laczmanska I et al.

Journal of Applied Genetics, 2019

Identification of cancer predisposition variants in apparently healthy individuals using a next-generation sequencing-based family genomics approach.

Karageorgos I et al.

Human Genomics, 2015

26092435 (PubMed )
Supplement: 40246_2015_34_MOESM1_ESM.xlsx › FamilyA

The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.

Tang X et al.

Nucleic Acids Research, 2014

25352556 (PubMed )
Supplement: supp_gku1005_nar-01266-met-n-2014-File012.xlsx › TCGA-AN-A049-01A.domain

High-resolution loss of heterozygosity screening implicates PTPRJ as a potential tumor suppressor gene that affects susceptibility to Non-Hodgkin's lymphoma.

Aya-Bonilla C et al.

Genes, Chromosomes & Cancer, 2013

The protein tyrosine phosphatase receptor type J is regulated by the pVHL-HIF axis in clear cell renal cell carcinoma.

Casagrande S et al.

The Journal of Pathology, 2013

Polymorphisms of protein tyrosine phosphatase CD148 influence FcγRIIA-dependent platelet activation and the risk of heparin-induced thrombocytopenia.

Rollin J et al.

Blood, 2012

Role of PTPRJ genotype in papillary thyroid carcinoma risk.

Iuliano R et al.

Endocrine-related Cancer, 2010

Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers.

Mita Y et al.

Journal of Cancer Research and Clinical Oncology, 2010

PTPRJ haplotypes and colorectal cancer risk.

Toland AE et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2008

Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer.

Lesueur F et al.

Human Molecular Genetics, 2005

The tyrosine phosphatase PTPRJ/DEP-1 genotype affects thyroid carcinogenesis.

Iuliano R et al.

Oncogene, 2004

Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers.

Ruivenkamp CA et al.

Nature Genetics, 2002

Centenarian Exomes as a Tool for Evaluating the Clinical Relevance of Germline Tumor Suppressor Mutations.

Balabanski L et al.

Technology in Cancer Research & Treatment, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."