Varaico: Literature-Extracted Genetic Variants

Gene:PTPRJ
Variant:p.C1239S
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PTPRJ

NM_002843.4:p.C1239S

Associated Papers

PTPRJ promotes osteoclast maturation and activity by inhibiting Cbl-mediated ubiquitination of NFATc1 in late osteoclastogenesis.

Shalev M et al.

The Febs Journal, 2021

CD148 tyrosine phosphatase promotes cadherin cell adhesion.

Takahashi K et al.

Plos One, 2014

Protein-tyrosine phosphatase DEP-1 controls receptor tyrosine kinase FLT3 signaling.

Arora D et al.

The Journal of Biological Chemistry, 2011

CD148 enhances platelet responsiveness to collagen by maintaining a pool of active Src family kinases.

Ellison S et al.

Journal of Thrombosis and Haemostasis : Jth, 2010

An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis.

Tarcic G et al.

Current Biology : Cb, 2009

The eighth fibronectin type III domain of protein tyrosine phosphatase receptor J influences the formation of protein complexes and cell localization.

Iuliano R et al.

Journal of Biochemistry, 2009

The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteins.

Iervolino A et al.

Cancer Research, 2006

Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1.

Palka HL et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."