Varaico: Literature-Extracted Genetic Variants

Gene:PTTG1
Variant:p.S183A
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PTTG1

NM_004219.4:p.S183A

Associated Papers

Phosphorylated PTTG1 switches its subcellular distribution and promotes β-catenin stabilization and subsequent transcription activity.

Zhang X et al.

Oncogene, 2023

Glycogen synthase kinase-3beta (GSK3beta) negatively regulates PTTG1/human securin protein stability, and GSK3beta inactivation correlates with securin accumulation in breast tumors.

Mora-Santos M et al.

The Journal of Biological Chemistry, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."