Varaico: Literature-Extracted Genetic Variants

Gene:PVR
Variant:p.A67T
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PVR

NM_006505.5:p.A67T

Associated Papers

Human stem cell-derived β cells expressing an optimized CD155 reduce cytotoxic immune cell function for application in type 1 diabetes.

Brown ME et al.

Science Advances, 2025

The Development of Monoclonal Antibodies Specific to the Soluble Form of CD155 in the Human Peripheral Blood.

Kinoshita S et al.

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 2025

Human Stem Cell-Derived β-cells Expressing An Optimized CD155 Reduce Cytotoxic Immune Cell Function for Application in Type 1 Diabetes.

Brown ME et al.

Biorxiv : the Preprint Server for Biology, 2025

Pathogenic germline variants in small cell lung cancer: A systematic review and meta-analysis.

Ul Haq S et al.

Hgg Advances, 2025

40308030 (PubMed )
Supplement: mmc2.xlsx › Table_S2

CD155 mutation (Ala67Thr) increases the binding affinity for and the signaling via an inhibitory immunoreceptor TIGIT.

Matsuo T et al.

Cancer Science, 2022

Essential role of autophagy in restricting poliovirus infection revealed by identification of an ATG7 defect in a poliomyelitis patient.

Brinck Andersen NS et al.

Autophagy, 2021

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

Fragoza R et al.

Nature Communications, 2019

31515488 (PubMed )
Supplement: 41467_2019_11959_MOESM11_ESM.xlsx › SD7_-_Drug_Targets

MicroRNA-655-3p and microRNA-497-5p inhibit cell proliferation in cultured human lip cells through the regulation of genes related to human cleft lip.

Gajera M et al.

Bmc Medical Genomics, 2019

31122291 (PubMed )
Supplement: 12920_2019_535_MOESM1_ESM.zip › 6_Human_Cleft_Lip_Table_S6__Not_Significant___R2.xlsx › Non-_significant

PVR/CD155 Ala67Thr Mutation and Cleft Lip/Palate.

Vieira AR et al.

The Journal of Craniofacial Surgery, 2018

Assay for identification of heterozygous single-nucleotide polymorphism (Ala67Thr) in human poliovirus receptor gene.

Nandi SS et al.

The Indian Journal of Medical Research, 2016

Genetic Determinants of Enterovirus Infections: Polymorphisms in Type 1 Diabetes and Innate Immune Genes in the MIDIA Study.

Witsø E et al.

Viral Immunology, 2015

Targeted exon capture and sequencing in sporadic amyotrophic lateral sclerosis.

Couthouis J et al.

Plos Genetics, 2014

Associations between single nucleotide polymorphisms in cellular viral receptors and attachment factor-related genes and humoral immunity to rubella vaccination.

Haralambieva IH et al.

Plos One, 2014

Mutation and association analysis of the PVR and PVRL2 genes in patients with non-syndromic cleft lip and palate.

Sözen MA et al.

Genetics and Molecular Biology, 2009

Ala67Thr mutation in the poliovirus receptor CD155 is a potential risk factor for vaccine and wild-type paralytic poliomyelitis.

Kindberg E et al.

Journal of Medical Virology, 2009

Denaturing high performance liquid chromatography: high throughput mutation screening in familial hypertrophic cardiomyopathy and SNP genotyping in motor neurone disease.

Yu B et al.

Journal of Clinical Pathology, 2005

The role of the polio virus receptor and the herpesvirus entry mediator B genes for the development of MS.

Rosche B et al.

Journal of Neuroimmunology, 2004

A polymorphism in the poliovirus receptor gene differs in motor neuron disease.

Saunderson R et al.

Neuroreport, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."