Varaico: Literature-Extracted Genetic Variants

Gene:PXN
Variant:p.S752P
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PXN

NM_001385981.1:p.S752P

Associated Papers

Transmembrane and cytoplasmic domains in integrin activation and protein-protein interactions (review).

Wegener KL et al.

Molecular Membrane Biology, 2008

Talin is required for integrin-mediated platelet function in hemostasis and thrombosis.

Petrich BG et al.

The Journal of Experimental Medicine, 2007

The MIG-2/integrin interaction strengthens cell-matrix adhesion and modulates cell motility.

Shi X et al.

The Journal of Biological Chemistry, 2007

Distinct involvement of beta3 integrin cytoplasmic domain tyrosine residues 747 and 759 in integrin-mediated cytoskeletal assembly and phosphotyrosine signaling.

Schaffner-Reckinger E et al.

The Journal of Biological Chemistry, 1998

Ser752 mutation to Pro or Ala in the beta3 integrin subunit differentially affects the kinetics of cell spreading to von Willebrand factor and fibrinogen.

Perrault C et al.

Cell Adhesion and Communication, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."