Varaico: Literature-Extracted Genetic Variants

Gene:PXN
Variant:p.I43F
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PXN

NM_001385981.1:p.I43F

Associated Papers

Mutational drivers of cancer cell migration and invasion.

Novikov NM et al.

British Journal of Cancer, 2021

Deciphering Mode of Action of Functionally Important Regions in the Intrinsically Disordered Paxillin (Residues 1-313) Using Its Interaction with FAT (Focal Adhesion Targeting Domain of Focal Adhesion Kinase).

Neerathilingam M et al.

Plos One, 2016

Paxillin mutations affect focal adhesions and lead to altered mitochondrial dynamics: relevance to lung cancer.

Kawada I et al.

Cancer Biology & Therapy, 2013

Somatic LMCD1 mutations promoted cell migration and tumor metastasis in hepatocellular carcinoma.

Chang CY et al.

Oncogene, 2012

No somatic genetic change in the paxillin gene in nonsmall-cell lung cancer.

Pallier K et al.

Molecular Carcinogenesis, 2009

Role of c-Met in cancer: emphasis on lung cancer.

Salgia R

Seminars in Oncology, 2009

Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion.

Jagadeeswaran R et al.

Cancer Research, 2008

MET molecular mechanisms and therapies in lung cancer.

Lawrence RE et al.

Cell Adhesion & Migration, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."