Varaico: Literature-Extracted Genetic Variants

Gene:PYCARD
Variant:p.K21E
Back to variants list

PYCARD

NM_013258.5:p.K21E

Associated Papers

Atomic mechanisms of full-length ASC-mediated inflammasome assembly.

Xue D et al.

Nature Communications, 2025

41298390 (PubMed )
Supplement: 41467_2025_65578_MOESM9_ESM.pdf

The Inflammasome Adaptor ASC Induces Procaspase-8 Death Effector Domain Filaments.

Vajjhala PR et al.

The Journal of Biological Chemistry, 2015

Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.

Lu A et al.

Cell, 2014

Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC.

Moriya M et al.

Biochemistry, 2005

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."