Associated Papers
One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids.
Geurts MH et al.
Nature Communications, 2023
The Inflammasome Adaptor ASC Induces Procaspase-8 Death Effector Domain Filaments.
Vajjhala PR et al.
The Journal of Biological Chemistry, 2015
Identification of multifaceted binding modes for pyrin and ASC pyrin domains gives insights into pyrin inflammasome assembly.
Vajjhala PR et al.
The Journal of Biological Chemistry, 2014
Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein.
Vajjhala PR et al.
The Journal of Biological Chemistry, 2012
Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC.
Moriya M et al.
Biochemistry, 2005
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