Associated Papers
A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation.
Vides EG et al.
Elife, 2022
Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis.
Heaton GR et al.
Neurobiology of Disease, 2020
The Parkinson's Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network.
Beilina A et al.
Cell Reports, 2020
Differences in Stability, Activity and Mutation Effects Between Human and Mouse Leucine-Rich Repeat Kinase 2.
Langston RG et al.
Neurochemical Research, 2019
RAB7L1-Mediated Relocalization of LRRK2 to the Golgi Complex Causes Centrosomal Deficits via RAB8A.
Madero-Pérez J et al.
Frontiers in Molecular Neuroscience, 2018
C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia.
Aoki Y et al.
Brain : a Journal of Neurology, 2017
RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk.
MacLeod DA et al.
Neuron, 2013
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