Varaico: Literature-Extracted Genetic Variants

Gene:RAB35
Variant:p.Q67L
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RAB35

NM_006861.7:p.Q67L

Associated Papers

A neurodevelopmental disorder associated with a loss-of-function missense mutation in RAB35.

Aguila A et al.

The Journal of Biological Chemistry, 2024

DENND2B activates Rab35 at the intercellular bridge, regulating cytokinetic abscission and tetraploidy.

Kumar R et al.

Cell Reports, 2023

IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules.

Bisi S et al.

Nature Communications, 2020

Rab35 controls cilium length, function and membrane composition.

Kuhns S et al.

Embo Reports, 2019

LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation.

Bae EJ et al.

Nature Communications, 2018

Rab35 GTPase: A Central Regulator of Phosphoinositides and F-actin in Endocytic Recycling and Beyond.

Klinkert K et al.

Traffic (copenhagen, Denmark), 2016

Identification of an oncogenic RAB protein.

Wheeler DB et al.

Science (new York, N.y.), 2015

piggyBac insertional mutagenesis screen identifies a role for nuclear RHOA in human ES cell differentiation.

Gayle S et al.

Stem Cell Reports, 2015

25866159 (PubMed )
Supplement: mmc1.pdf

Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation.

Langemeyer L et al.

Elife, 2014

A Small Ras-like protein Ray/Rab1c modulates the p53-regulating activity of PRPK.

Abe Y et al.

Biochemical and Biophysical Research Communications, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."