Associated Papers
Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved peptide motif.
Waschbüsch D et al.
Structure (london, England : 1993), 2026
Functional and Structural Insights Into Complex Formation Between OPTN Leucine Zipper Domain and RAB8A.
Okatsu K et al.
Genes to Cells : Devoted to Molecular & Cellular Mechanisms, 2025
Rab7a is an enhancer of TPC2 activity regulating melanoma progression through modulation of the GSK3β/β-Catenin/MITF-axis.
Abrahamian C et al.
Nature Communications, 2024
A direct interaction between CENTLEIN and RABIN8 is required for primary cilium formation.
Li L et al.
Acta Biochimica Et Biophysica Sinica, 2023
Rab8 and TNPO1 are ciliary transport adaptors for GTPase Arl13b by interacting with its RVEP motif containing ciliary targeting sequence.
Mahajan D et al.
The Journal of Biological Chemistry, 2023
Rgp1 contributes to craniofacial cartilage development and Rab8a-mediated collagen II secretion.
Ritter DJ et al.
Frontiers in Endocrinology, 2023
CEP290 is essential for the initiation of ciliary transition zone assembly.
Wu Z et al.
Plos Biology, 2020
TMEM135 regulates primary ciliogenesis through modulation of intracellular cholesterol distribution.
Maharjan Y et al.
Embo Reports, 2020
The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A.
Rivero-Ríos P et al.
The Journal of Biological Chemistry, 2019
M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells.
Sirohi K et al.
Autophagy, 2013
Accumulation of the Raf-1 kinase inhibitory protein (Rkip) is associated with Cep290-mediated photoreceptor degeneration in ciliopathies.
Murga-Zamalloa CA et al.
The Journal of Biological Chemistry, 2011
The AP-1 clathrin adaptor facilitates cilium formation and functions with RAB-8 in C. elegans ciliary membrane transport.
Kaplan OI et al.
Journal of Cell Science, 2010
Interaction of retinitis pigmentosa GTPase regulator (RPGR) with RAB8A GTPase: implications for cilia dysfunction and photoreceptor degeneration.
Murga-Zamalloa CA et al.
Human Molecular Genetics, 2010
Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice.
Chi ZL et al.
Human Molecular Genetics, 2010
Sensory signaling-dependent remodeling of olfactory cilia architecture in C. elegans.
Mukhopadhyay S et al.
Developmental Cell, 2008