Associated Papers
Proximity-based proteomics (BioID) uncovers the Rho GTPase interactome in kidney podocytes.
Ibrahim S et al.
Frontiers in Cell and Developmental Biology, 2025
Clinical profiling of MRD48 and functional characterization of two novel pathogenic RAC1 variants.
Priolo M et al.
European Journal of Human Genetics : Ejhg, 2023
In silico identification and characterization of small-molecule inhibitors specific to RhoG/Rac1 signaling pathway.
Dipankar P et al.
Journal of Biomolecular Structure & Dynamics, 2023
Control of CRK-RAC1 activity by the miR-1/206/133 miRNA family is essential for neuromuscular junction function.
Klockner I et al.
Nature Communications, 2022
Loss of Zic3 impairs planar cell polarity leading to abnormal left-right signaling, heart defects and neural tube defects.
Bellchambers HM et al.
Human Molecular Genetics, 2021
Development and Validation of Targeted Gene Sequencing Panel Based Companion Diagnostic for Korean Patients with Solid Tumors.
Min BJ et al.
Cancers, 2021
Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development.
Guo S et al.
Theranostics, 2021
Deregulated Rac1 Activity in Neural Crest Controls Cell Proliferation, Migration and Differentiation During Midbrain Development.
Gahankari A et al.
Frontiers in Cell and Developmental Biology, 2021
RAC1mutation is not a predictive biomarker for PI3'-kinase-β-selective pathway-targeted therapy.
Foth M et al.
Pigment Cell & Melanoma Research, 2020
Genomic landscape of platinum resistant and sensitive testicular cancers.
Loveday C et al.
Nature Communications, 2020
Different signaling and functionality of Rac1 and Rac1b in the progression of lung adenocarcinoma.
Seiz JR et al.
Biological Chemistry, 2020
Comprehensive genomic profiling of high-grade serous ovarian carcinoma from Chinese patients identifies co-occurring mutations in the Ras/Raf pathway with TP53.
Zhong F et al.
Cancer Medicine, 2019
KRAS: The Critical Driver and Therapeutic Target for Pancreatic Cancer.
Waters AM et al.
Cold Spring Harbor Perspectives in Medicine, 2018
Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers.
Pozdeyev N et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2018
STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap.
Woroniuk A et al.
Nature Communications, 2018
A KRAS wild type mutational status confers a survival advantage in pancreatic ductal adenocarcinoma.
Windon AL et al.
Journal of Gastrointestinal Oncology, 2018
The Rac GTPase in Cancer: From Old Concepts to New Paradigms.
Kazanietz MG et al.
Cancer Research, 2017
Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras.
Wang T et al.
Cell, 2017
NADPH Oxidase Contributes to Photoreceptor Degeneration in Constitutively Active RAC1 Mice.
Song H et al.
Investigative Ophthalmology & Visual Science, 2016
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
Chang MT et al.
Nature Biotechnology, 2016
ClipR-59 interacts with Elmo2 and modulates myoblast fusion.
Sun Y et al.
The Journal of Biological Chemistry, 2015
Transgenic expression of constitutively active RAC1 disrupts mouse rod morphogenesis.
Song H et al.
Investigative Ophthalmology & Visual Science, 2014
A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion.
Wawrzyniak JA et al.
Cell Reports, 2013
Transforming mutations of RAC guanosine triphosphatases in human cancers.
Kawazu M et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013
Clathrin-independent endocytosis used by the IL-2 receptor is regulated by Rac1, Pak1 and Pak2.
Grassart A et al.
Embo Reports, 2008
The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling.
Soderling SH et al.
Nature Cell Biology, 2002