Varaico: Literature-Extracted Genetic Variants

Gene:RAC1
Variant:p.C189S
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RAC1

NM_006908.5:p.C189S

Associated Papers

Inhibition of Unc119b improves insulin sensitivity through potentiation of Rac1 activation in skeletal muscle and brown adipose tissue.

Mittal A et al.

Molecular Metabolism, 2025

Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression.

Mitin N et al.

Nature Structural & Molecular Biology, 2007

Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1.

Miyano K et al.

The Journal of Biological Chemistry, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."