Varaico: Literature-Extracted Genetic Variants

Gene:RAC2
Variant:p.Q61L
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RAC2

NM_002872.5:p.Q61L

Associated Papers

Cyclized Peptide Inhibitors of the Small G Protein Cdc42 Mimic Binding of Effector Proteins.

Murphy NP et al.

Biochemistry, 2026

Combined Immunodeficiency Caused by a Novel De Novo Gain-of-Function RAC2 Mutation.

Zhang L et al.

Journal of Clinical Immunology, 2022

Dominant activating RAC2 mutation with lymphopenia, immunodeficiency, and cytoskeletal defects.

Hsu AP et al.

Blood, 2019

A monoallelic activating mutation in RAC2 resulting in a combined immunodeficiency.

Lougaris V et al.

The Journal of Allergy and Clinical Immunology, 2019

The proto-oncogene KRAS and BRAF profiles and some clinical characteristics in colorectal cancer in the Turkish population.

Ozen F et al.

Genetic Testing and Molecular Biomarkers, 2013

Detection of KRAS and BRAF mutations in colorectal carcinoma roles for high-sensitivity locked nucleic acid-PCR sequencing and broad-spectrum mass spectrometry genotyping.

Arcila M et al.

The Journal of Molecular Diagnostics : Jmd, 2011

Fluoride complexes of oncogenic Ras mutants to study the Ras-RasGap interaction.

Gremer L et al.

Biological Chemistry, 2008

The novel ankyrin-repeat containing kinase ARCK-1 acts as a suppressor of the Spalten signaling pathway during Dictyostelium development.

Aubry L et al.

Developmental Biology, 2003

Ras superfamily monomeric G proteins in carcinoma cell motility.

Oxford G et al.

Cancer Letters, 2003

Biochemical and biological characterization of a human Rac2 GTPase mutant associated with phagocytic immunodeficiency.

Gu Y et al.

The Journal of Biological Chemistry, 2001

Mutant Rac1B expression in Dictyostelium: effects on morphology, growth, endocytosis, development, and the actin cytoskeleton.

Palmieri SJ et al.

Cell Motility and the Cytoskeleton, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."