Varaico: Literature-Extracted Genetic Variants

Gene:RAC2
Variant:p.P29L
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RAC2

NM_002872.5:p.P29L

Associated Papers

A Novel Gain-of-Function RAC2 Variant (p.Y64H) Associated With Lymphopenia and Leukopenia.

Haliloğlu Y et al.

Pediatric Blood & Cancer, 2026

Accurate affinity models for SH2 domains from peptide binding assays and free-energy regression.

Gagoski D et al.

Protein Science : a Publication of the Protein Society, 2025

41088778 (PubMed )
Supplement: PRO-34-e70317-s008.xlsx › _S6_-_PTMVar_-_Fyn

Accurate sequence-to-affinity models for SH2 domains from multi-round peptide binding assays coupled with free-energy regression.

Gagoski D et al.

Biorxiv : the Preprint Server for Biology, 2025

39764007 (PubMed )
Supplement: media-1.xlsx › _S6_-_PTMVar_-_Fyn

Combined Immunodeficiency Caused by a Novel De Novo Gain-of-Function RAC2 Mutation.

Zhang L et al.

Journal of Clinical Immunology, 2022

Transforming mutations of RAC guanosine triphosphatases in human cancers.

Kawazu M et al.

Proceedings of the National Academy of Sciences of the United States of America, 2013

RAC1P29S is a spontaneously activating cancer-associated GTPase.

Davis MJ et al.

Proceedings of the National Academy of Sciences of the United States of America, 2013

A landscape of driver mutations in melanoma.

Hodis E et al.

Cell, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."