Varaico: Literature-Extracted Genetic Variants

Gene:RACK1
Variant:p.Y302F
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RACK1

NM_006098.5:p.Y302F

Associated Papers

Roles of RACK1 in centrosome regulation and carcinogenesis.

Yoshino Y et al.

Cellular Signalling, 2022

RACK1 regulates centriole duplication by controlling localization of BRCA1 to the centrosome in mammary tissue-derived cells.

Yoshino Y et al.

Oncogene, 2019

Phosphorylation of RACK1 on tyrosine 52 by c-Abl is required for insulin-like growth factor I-mediated regulation of focal adhesion kinase.

Kiely PA et al.

The Journal of Biological Chemistry, 2009

Tyrosine 302 in RACK1 is essential for insulin-like growth factor-I-mediated competitive binding of PP2A and beta1 integrin and for tumor cell proliferation and migration.

Kiely PA et al.

The Journal of Biological Chemistry, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."