Varaico: Literature-Extracted Genetic Variants

Gene:RAD18
Variant:p.C207F
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RAD18

NM_020165.4:p.C207F

Associated Papers

RAD18 mediates DNA double-strand break-induced ubiquitination of chromatin protein.

Mustofa MK et al.

Journal of Biochemistry, 2021

Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA.

Despras E et al.

Nature Communications, 2016

Asymmetric nature of two subunits of RAD18, a RING-type ubiquitin ligase E3, in the human RAD6A-RAD18 ternary complex.

Masuda Y et al.

Nucleic Acids Research, 2012

NBS1 recruits RAD18 via a RAD6-like domain and regulates Pol η-dependent translesion DNA synthesis.

Yanagihara H et al.

Molecular Cell, 2011

Human RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double strand breaks.

Inagaki A et al.

Plos One, 2011

RAD18 transmits DNA damage signalling to elicit homologous recombination repair.

Huang J et al.

Nature Cell Biology, 2009

RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40.

Simpson LJ et al.

Embo Reports, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."