Associated Papers
The E3 ligase RAD18-mediated ubiquitination of henipavirus matrix protein promotes its nuclear-cytoplasmic trafficking and viral egress.
Jin D et al.
Emerging Microbes & Infections, 2025
Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA.
Despras E et al.
Nature Communications, 2016
Rad18 is required for functional interactions between FANCD2, BRCA2, and Rad51 to repair DNA topoisomerase 1-poisons induced lesions and promote fork recovery.
Tripathi K et al.
Oncotarget, 2016
RAD18 Is a Maternal Limiting Factor Silencing the UV-Dependent DNA Damage Checkpoint in Xenopus Embryos.
Kermi C et al.
Developmental Cell, 2015
A non-catalytic role of DNA polymerase η in recruiting Rad18 and promoting PCNA monoubiquitination at stalled replication forks.
Durando M et al.
Nucleic Acids Research, 2013
Asymmetric nature of two subunits of RAD18, a RING-type ubiquitin ligase E3, in the human RAD6A-RAD18 ternary complex.
Masuda Y et al.
Nucleic Acids Research, 2012
NBS1 recruits RAD18 via a RAD6-like domain and regulates Pol η-dependent translesion DNA synthesis.
Yanagihara H et al.
Molecular Cell, 2011
Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition.
Palle K et al.
Cell Cycle (georgetown, Tex.), 2011
The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI.
Williams SA et al.
Blood, 2011
Human RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double strand breaks.
Inagaki A et al.
Plos One, 2011
Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway.
Song IY et al.
The Journal of Biological Chemistry, 2010
RAD18 transmits DNA damage signalling to elicit homologous recombination repair.
Huang J et al.
Nature Cell Biology, 2009
RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40.
Simpson LJ et al.
Embo Reports, 2006
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