Varaico: Literature-Extracted Genetic Variants

Gene:RAD51
Variant:p.Y54F
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RAD51

NM_002875.5:p.Y54F

Associated Papers

The protein phosphatase EYA4 promotes homologous recombination (HR) through dephosphorylation of tyrosine 315 on RAD51.

de la Peña Avalos B et al.

Nucleic Acids Research, 2024

New Phosphorylation Sites of Rad51 by c-Met Modulates Presynaptic Filament Stability.

Chabot T et al.

Cancers, 2019

ABL tyrosine kinases: evolution of function, regulation, and specificity.

Colicelli J

Science Signaling, 2010

Detection of c-Abl kinase-promoted phosphorylation of Rad51 by specific antibodies reveals that Y54 phosphorylation is dependent on that of Y315.

Popova M et al.

Febs Letters, 2009

c-ABL tyrosine kinase stabilizes RAD51 chromatin association.

Shimizu H et al.

Biochemical and Biophysical Research Communications, 2009

BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance.

Slupianek A et al.

Molecular Cell, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."