Associated Papers
Dissecting the RAD51-BRC4 Interaction Landscape through Integrative Molecular Simulations and Experimental Biophysics.
Bresciani V et al.
Journal of Chemical Information and Modeling, 2025
In silico structural analysis of Oryza sativa RAD51 reveals key interactions for nucleoprotein filament assembly and regulation.
Azeem A et al.
Plos One, 2025
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer.
Myers SH et al.
European Journal of Medicinal Chemistry, 2024
Isolation and Characterization of Monomeric Human RAD51: A Novel Tool for Investigating Homologous Recombination in Cancer.
Rinaldi F et al.
Angewandte Chemie (international Ed. in English), 2023
Congenital mirror movements are associated with defective polymerisation of RAD51.
Trouillard O et al.
Journal of Medical Genetics, 2023
Structural insights into BCDX2 complex function in homologous recombination.
Rawal Y et al.
Nature, 2023
Network Analysis of RAD51 Proteins in Metazoa and the Evolutionary Relationships With Their Archaeal Homologs.
Jiang S et al.
Frontiers in Genetics, 2018
Structure-activity relationship of the peptide binding-motif mediating the BRCA2:RAD51 protein-protein interaction.
Scott DE et al.
Febs Letters, 2016
Nascent DNA synthesis during homologous recombination is synergistically promoted by the rad51 recombinase and DNA homology.
Mundia MM et al.
Genetics, 2014
Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.
Esashi F et al.
Nature Structural & Molecular Biology, 2007
Dynamic control of Rad51 recombinase by self-association and interaction with BRCA2.
Yu DS et al.
Molecular Cell, 2003
BRCA2 keeps Rad51 in line. High-fidelity homologous recombination prevents breast and ovarian cancer?
Powell SN et al.
Molecular Cell, 2002
Insights into DNA recombination from the structure of a RAD51-BRCA2 complex.
Pellegrini L et al.
Nature, 2002
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