Varaico: Literature-Extracted Genetic Variants

Gene:RAD51
Variant:p.T103T
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RAD51

NM_002875.5:p.T103T

Associated Papers

High-throughput mapping of 6,888 RAD51D variants identifies distinct biochemical functions needed for homologous recombination and olaparib response.

Darrah KE et al.

Biorxiv : the Preprint Server for Biology, 2026

41542474 (PubMed )
Supplement: media-1.xlsx › Sup._Table_5_MAVE_SNVs_

The F-Box Domain-Dependent Activity of EMI1 Regulates PARPi Sensitivity in Triple-Negative Breast Cancers.

Marzio A et al.

Molecular Cell, 2019

Network Analysis of RAD51 Proteins in Metazoa and the Evolutionary Relationships With Their Archaeal Homologs.

Jiang S et al.

Frontiers in Genetics, 2018

Homologous recombination defects and how they affect replication fork maintenance.

Son MY et al.

Aims Genetics, 2018

RAD51 as a potential surrogate marker for DNA repair capacity in solid malignancies.

Gachechiladze M et al.

International Journal of Cancer, 2017

Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function.

Murfuni I et al.

Plos Genetics, 2013

Expression and regulation of RAD51 mediate cellular responses to chemotherapeutics.

Yang Z et al.

Biochemical Pharmacology, 2012

Regulation of homologous recombination in eukaryotes.

Heyer WD et al.

Annual Review of Genetics, 2010

The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair.

Sørensen CS et al.

Nature Cell Biology, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."