Varaico: Literature-Extracted Genetic Variants

Gene:RAD51
Variant:p.D149N
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RAD51

NM_002875.5:p.D149N

Associated Papers

Homologous recombination, cancer and the 'RAD51 paradox'.

Matos-Rodrigues G et al.

Nar Cancer, 2021

Characterization of a potent dominant negative mutant variant of Rad51 in Ustilago maydis.

Sutherland JH et al.

Dna Repair, 2019

Variation in RAD51 details a hub of functions: opportunities to advance cancer diagnosis and therapy.

van der Zon NL et al.

F1000research, 2018

Network Analysis of RAD51 Proteins in Metazoa and the Evolutionary Relationships With Their Archaeal Homologs.

Jiang S et al.

Frontiers in Genetics, 2018

Defects in recombination activity caused by somatic and germline mutations in the multimerization/BRCA2 binding region of human RAD51 protein.

Silva MC et al.

Dna Repair, 2017

RAD51 variant proteins from human lung and kidney tumors exhibit DNA strand exchange defects.

Silva MC et al.

Dna Repair, 2016

Tumor-associated mutations in a conserved structural motif alter physical and biochemical properties of human RAD51 recombinase.

Chen J et al.

Nucleic Acids Research, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."