Associated Papers
Circulating cell-free DNA profiling reveals ancestry-dependent genetic variation in metastatic prostate cancer.
Maleknia S et al.
Molecular Biomedicine, 2026
BRCA2 prevents PARPi-mediated PARP1 retention to protect RAD51 filaments.
Lahiri S et al.
Nature, 2025
The BRCA2 R2645G variant increases DNA binding and induces hyper-recombination.
Alvaro-Aranda L et al.
Nucleic Acids Research, 2024
RAD51 bypasses the CMG helicase to promote replication fork reversal.
Liu W et al.
Science (new York, N.y.), 2023
Genomic Signatures from Clinical Tumor Sequencing in Patients with Breast Cancer Having Germline BRCA1/2 Mutation.
Kim JW et al.
Cancer Research and Treatment, 2023
BAT26 Only Microsatellite Instability with High Tumor Mutation Burden-A Rare Entity Associated with PTEN Protein Loss and High PD-L1 Expression.
Kang SY et al.
International Journal of Molecular Sciences, 2022
Epigenetic and genomic profiling of chordoid meningioma: implications for clinical management.
Daoud EV et al.
Acta Neuropathologica Communications, 2022
Homologous Recombination Deficiency: Cancer Predispositions and Treatment Implications.
Toh M et al.
The Oncologist, 2021
Homologous recombination, cancer and the 'RAD51 paradox'.
Matos-Rodrigues G et al.
Nar Cancer, 2021
The canine RAD51 mutation leads to the attenuation of interaction with PALB2.
Uemura M et al.
Veterinary and Comparative Oncology, 2020
Characterization of a potent dominant negative mutant variant of Rad51 in Ustilago maydis.
Sutherland JH et al.
Dna Repair, 2019
Distinct roles of ATM and ATR in the regulation of ARP8 phosphorylation to prevent chromosome translocations.
Sun J et al.
Elife, 2018
Variation in RAD51 details a hub of functions: opportunities to advance cancer diagnosis and therapy.
van der Zon NL et al.
F1000research, 2018
Network Analysis of RAD51 Proteins in Metazoa and the Evolutionary Relationships With Their Archaeal Homologs.
Jiang S et al.
Frontiers in Genetics, 2018
Defects in recombination activity caused by somatic and germline mutations in the multimerization/BRCA2 binding region of human RAD51 protein.
Silva MC et al.
Dna Repair, 2017
The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation.
Galick HA et al.
Oncotarget, 2017
Frequent inactivating germline mutations in DNA repair genes in patients with Ewing sarcoma.
Brohl AS et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2017
The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype.
Marsden CG et al.
Plos Genetics, 2016
RAD51 variant proteins from human lung and kidney tumors exhibit DNA strand exchange defects.
Silva MC et al.
Dna Repair, 2016
Tumor-associated mutations in a conserved structural motif alter physical and biochemical properties of human RAD51 recombinase.
Chen J et al.
Nucleic Acids Research, 2015