Associated Papers
Pathogenic variation in human DNA damage repair genes was originated from the evolutionary process of modern humans.
Li J et al.
Genes & Diseases, 2026
RAD51-Related Fanconi Anemia: Expanding the Phenotypic Spectrum and Strong Association With VACTERL.
Altintas B et al.
Clinical Genetics, 2025
Pathogenic variants in human DNA damage repair genes mostly arose after the latest human out-of-Africa migration.
He J et al.
Frontiers in Genetics, 2024
Fanconi anemia-associated mutation in RAD51 compromises the coordinated action of DNA-binding and ATPase activities.
Liu S et al.
The Journal of Biological Chemistry, 2023
RAD51 bypasses the CMG helicase to promote replication fork reversal.
Liu W et al.
Science (new York, N.y.), 2023
A novel RAD51 variant resulting in Fanconi anemia identified in an infant with multiple congenital anomalies.
Geilmann S et al.
Clinical Case Reports, 2023
Are transient protein-protein interactions more dispensable?
Ghadie MA et al.
Plos Computational Biology, 2022
Mutation Edgotype Drives Fitness Effect in Human.
Ghadie M et al.
Frontiers in Bioinformatics, 2021
Proteolytic control of genome integrity at the replication fork.
Rageul J et al.
Dna Repair, 2019
Estimating dispensable content in the human interactome.
Ghadie M et al.
Nature Communications, 2019
A Japanese patient with RAD51-associated Fanconi anemia.
Takenaka S et al.
American Journal of Medical Genetics. Part A, 2019
Characterization of a potent dominant negative mutant variant of Rad51 in Ustilago maydis.
Sutherland JH et al.
Dna Repair, 2019
Variation in RAD51 details a hub of functions: opportunities to advance cancer diagnosis and therapy.
van der Zon NL et al.
F1000research, 2018
Network Analysis of RAD51 Proteins in Metazoa and the Evolutionary Relationships With Their Archaeal Homologs.
Jiang S et al.
Frontiers in Genetics, 2018
Homologous recombination defects and how they affect replication fork maintenance.
Son MY et al.
Aims Genetics, 2018
Defects in recombination activity caused by somatic and germline mutations in the multimerization/BRCA2 binding region of human RAD51 protein.
Silva MC et al.
Dna Repair, 2017
Fanconi-Anemia-Associated Mutations Destabilize RAD51 Filaments and Impair Replication Fork Protection.
Zadorozhny K et al.
Cell Reports, 2017
Recent insights into the molecular basis of Fanconi anemia: genes, modifiers, and drivers.
Cheung RS et al.
International Journal of Hematology, 2017
Recent discoveries in the molecular pathogenesis of the inherited bone marrow failure syndrome Fanconi anemia.
Mamrak NE et al.
Blood Reviews, 2017
High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy.
Short JM et al.
Nucleic Acids Research, 2016
Interplay between Fanconi anemia and homologous recombination pathways in genome integrity.
Michl J et al.
The Embo Journal, 2016
A novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD51.
Ameziane N et al.
Nature Communications, 2015