Varaico: Literature-Extracted Genetic Variants

Gene:RAD51C
Variant:p.D242N
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RAD51C

NM_058216.3:p.D242N

Associated Papers

Comprehensive RAD51C ovarian cancer variant analysis uncouples homologous recombination and replicative functions.

Rein HL et al.

Nature Communications, 2025

Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C.

Hu C et al.

Cancer Research, 2023

Homologous recombination-deficient mutation cluster in tumor suppressor RAD51C identified by comprehensive analysis of cancer variants.

Prakash R et al.

Proceedings of the National Academy of Sciences of the United States of America, 2022

36099300 (PubMed )
Supplement: pnas.2202727119.sapp.pdf

Integration of tumour sequencing and case-control data to assess pathogenicity of RAD51C missense variants in familial breast cancer.

Lim BWX et al.

Npj Breast Cancer, 2022

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