Varaico: Literature-Extracted Genetic Variants

Gene:RAD51C
Variant:p.R249H
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RAD51C

NM_058216.3:p.R249H

Associated Papers

Comprehensive RAD51C ovarian cancer variant analysis uncouples homologous recombination and replicative functions.

Rein HL et al.

Nature Communications, 2025

40670332 (PubMed )
Supplement: 41467_2025_61283_MOESM3_ESM.xlsx › Sheet1

Homologous recombination-deficient mutation cluster in tumor suppressor RAD51C identified by comprehensive analysis of cancer variants.

Prakash R et al.

Proceedings of the National Academy of Sciences of the United States of America, 2022

Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Peng W et al.

Nature Communications, 2022

35273153 (PubMed )
Supplement: 41467_2022_28840_MOESM7_ESM.xlsx › Sheet1

Integration of tumour sequencing and case-control data to assess pathogenicity of RAD51C missense variants in familial breast cancer.

Lim BWX et al.

Npj Breast Cancer, 2022

35039523 (PubMed )
Supplement: 41523_2021_373_MOESM1_ESM.pdf

An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Lin J et al.

Frontiers in Immunology, 2022

36505399 (PubMed )
Supplement: Table_2.xlsx › vars

Patterns and functional implications of rare germline variants across 12 cancer types.

Lu C et al.

Nature Communications, 2015

26689913 (PubMed )
Supplement: ncomms10086-s13.xlsx › supplementary_data_12
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