Varaico: Literature-Extracted Genetic Variants

Gene:RAF1
Variant:p.E545K
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RAF1

NM_002880.4:p.E545K

Associated Papers

Identification of Somatic Genetic Variants in Superficial Vascular Malformations by Liquid Biopsy in a Cohort of 88 Patients from a French Hospital.

El Sissy FN et al.

Molecular Diagnosis & Therapy, 2025

Somatic Mutations in Latin American Breast Cancer Patients: A Systematic Review and Meta-Analysis.

Martínez-Nava GA et al.

Diagnostics (basel, Switzerland), 2024

Genomic profiling informs diagnoses and treatment in vascular anomalies.

Li D et al.

Nature Medicine, 2023

Evaluation of the Mutation Profile via Next-Generation Sequencing in a Turkish Population With Non-small Cell Lung Cancer.

Kahraman Çetin N et al.

Balkan Medical Journal, 2021

NGS-based liquid biopsy profiling identifies mechanisms of resistance to ALK inhibitors: a step toward personalized NSCLC treatment.

Sánchez-Herrero E et al.

Molecular Oncology, 2021

34058070 (PubMed )
Supplement: MOL2-15-2363-s001.docx

Induction of PIK3CA alterations during neoadjuvant letrozole may improve outcome in postmenopausal breast cancer patients.

Skriver SK et al.

Breast Cancer Research and Treatment, 2020

Signatures of somatic mutations and gene expression from p16INK4A positive head and neck squamous cell carcinomas (HNSCC).

Saba NF et al.

Plos One, 2020

Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing.

Oliveira DM et al.

Oncotarget, 2018

Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience.

Gong J et al.

Oncotarget, 2017

Study of PIK3CA, BRAF, and KRAS mutations in breast carcinomas among Chinese women in Qinghai.

Wang YL et al.

Genetics and Molecular Research : Gmr, 2015

Incomplete inhibition of phosphorylation of 4E-BP1 as a mechanism of primary resistance to ATP-competitive mTOR inhibitors.

Ducker GS et al.

Oncogene, 2014

Characteristics and prevalence of KRAS, BRAF, and PIK3CA mutations in colorectal cancer by high-resolution melting analysis in Taiwanese population.

Hsieh LL et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2012

Molecular profiling of patients with colorectal cancer and matched targeted therapy in phase I clinical trials.

Dienstmann R et al.

Molecular Cancer Therapeutics, 2012

Mutational analysis of cutaneous squamous cell carcinomas and verrucal keratosis in patients taking BRAF inhibitors.

Anforth R et al.

Pigment Cell & Melanoma Research, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."